与青少年早期开始注射吸毒相关的因素：对干预项目的启示
Factors associated with early adolescent initiation into injection drug use: implications for intervention programs.
作者信息
Miller Cari L, Strathdee Steffanie A, Kerr Thomas, Li Kathy, Wood Evan
机构信息
British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, British Columbia, Canada.
出版信息
J Adolesc Health. 2006 Apr;38(4):462-4. doi: 10.1016/j.jadohealth.2005.03.004.
This study explores factors associated with early adolescent (aged < or = 16 years) initiation into injection drug use among young (< or = 29 years) injection drug users (IDUs). Data were collected through the Vancouver Injection Drug Users Study (VIDUS). Since 1996, 542 participants aged 29 years and younger have been enrolled and followed. In total, 205 (38%) young participants were initiated at age 16 years or younger. The proportion of young initiators was greater among: females, adjusted odds ratio [AOR]: 1.63 (95% confidence interval [CI]: 1.09-2.44); sex workers, AOR: 1.61 (CI: 1.11-2.31); binge drug users, AOR: 1.45 (CI: 1.01-2.08); and those who have been in juvenile detention or jail, AOR: 1.78 (CI: 1.16-2.66). Early initiates were more likely to be infected with human immunodeficiency virus (HIV), OR: 2.6 (CI: 1.3-5.0) and hepatitis C virus (HCV), OR: 2.6 (CI: 1.3-5.0). Targeted early interventions are required, specifically designed for and in collaboration with girls and young women.
本研究探讨了年轻（≤29岁）注射吸毒者（IDU）中与青少年早期（年龄≤16岁）开始注射吸毒相关的因素。数据通过温哥华注射吸毒者研究（VIDUS）收集。自1996年以来，已招募并跟踪了542名年龄在29岁及以下的参与者。总共有205名（38%）年轻参与者在16岁或更年轻时开始吸毒。在以下人群中，年轻吸毒起始者的比例更高：女性，调整后的优势比[AOR]：1.63（95%置信区间[CI]：1.09 - 2.44）；性工作者，AOR：1.61（CI：1.11 - 2.31）；药物滥用者，AOR：1.45（CI：1.01 - 2.08）；以及曾被拘留或监禁的青少年，AOR：1.78（CI：1.16 - 2.66）。早期吸毒起始者感染人类免疫缺陷病毒（HIV）的可能性更高，比值比（OR）：2.6（CI：1.3 - 5.0），感染丙型肝炎病毒（HCV）的可能性也更高，OR：2.6（CI：1.3 - 5.0）。需要开展有针对性的早期干预措施，专门为女孩和年轻女性设计并与她们合作开展。
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