Avram Anca M, Mackie Gavin C, Schneider Bryan J, Kalemkerian Gregory P, Shulkin Barry L
Division of Nuclear Medicine, Department of Radiology, University of Michigan Medical Center, Ann Arbor, 48109, USA.
Clin Nucl Med. 2006 Apr;31(4):197-200. doi: 10.1097/01.rlu.0000204200.66112.a9.
A patient who presented with weight loss and recurrent left lower lobe pneumonia was diagnosed with endobronchial carcinoid. Chest CT scan demonstrated extensive mediastinal and hilar lymphadenopathy suggesting stage IIIB disease, but radionuclide imaging with In-111 pentetreotide and F-18 FDG PET diagnosed 2 distinct pathologic processes based on functional differences between neuroendocrine tumors (expressing somatostatin receptors) and sarcoidosis (intensely FDG-avid). The possible association of carcinoid with sarcoidosis and sarcoid-like reactions in regional lymph nodes should always be considered, and the staging process should include both anatomic and functional imaging and biopsy confirmation of suspected metastatic lesions.
一名出现体重减轻和复发性左肺下叶肺炎的患者被诊断为支气管内类癌。胸部CT扫描显示广泛的纵隔和肺门淋巴结肿大，提示为IIIB期疾病，但使用铟-111喷替肽和氟-18氟代脱氧葡萄糖PET进行的放射性核素成像根据神经内分泌肿瘤（表达生长抑素受体）和结节病（强烈摄取氟代脱氧葡萄糖）之间的功能差异诊断出两种不同的病理过程。应始终考虑类癌与结节病以及区域淋巴结中类结节样反应的可能关联，分期过程应包括解剖学和功能成像以及对疑似转移病变的活检确认。
