Kim Hae-Rim, Kim Sung-Dong, Kim Sang-Hyon, Yoon Chong-Hyun, Lee Sang-Heon, Park Sung-Hwan, Kim Ho-Youn
Department of Internal Medicine, School of Medicine, Konkuk University, 4-12 Hwayang-dong, Gwangjin-gu, Seoul 143-729, South Korea.
Clin Rheumatol. 2007 May;26(5):801-3. doi: 10.1007/s10067-006-0239-9. Epub 2006 Mar 15.
Cytomegalovirus (CMV) retinitis rarely occurs in patients with connective tissue disease. We present a rare case of CMV retinitis in a patient with dermatomyositis. A 38-year-old man was admitted due to blurred vision and floaters of right eye. He had been diagnosed with dermatomyositis and taken prednisolone and immunosuppressive agents for 10 months. He was diagnosed as having CMV retinitis based upon ophthalmologic examination, decreased CD4+T cell count, and positive IgM anti-CMV antibody. Intravenous ganciclovir was administrated with cessation of immunosuppressive agents for 40 days and the lesion did not progress. This is the first report of a CMV retinitis that developed in a patient with dermatomyositis.
巨细胞病毒(CMV)视网膜炎在结缔组织病患者中很少发生。我们报告了一例皮肌炎患者发生CMV视网膜炎的罕见病例。一名38岁男性因右眼视力模糊和眼前有漂浮物入院。他被诊断为皮肌炎,已服用泼尼松龙和免疫抑制剂10个月。根据眼科检查、CD4 + T细胞计数降低以及抗CMV IgM抗体阳性,他被诊断为患有CMV视网膜炎。给予静脉注射更昔洛韦,并停用免疫抑制剂40天,病变未进展。这是首例关于皮肌炎患者发生CMV视网膜炎的报告。