无色杆菌中的氰化物抗性II. 氰化物抗性机制
Cyanide Resistance in Achromobacter II. Mechanism of Cyanide Resistance.
作者信息
Oka T, Arima K
机构信息
Laboratory of Fermentation, Department of Agricultural Chemistry, University of Tokyo, Tokyo, Japan.
出版信息
J Bacteriol. 1965 Sep;90(3):744-7. doi: 10.1128/jb.90.3.744-747.1965.
Oka, Tetuo (University of Tokyo, Tokyo, Japan), and Kei Arima. Cyanide resistance in Achromobacter. II. Mechanism of cyanide resistance. J. Bacteriol. 90:744-747. 1965.-Photochemical data showed that the only oxidase found in the cyanide-sensitive cells of Achromobacter was cytochrome o, and that cyanide-resistant cells contained at least two oxidases. The oxidase responsible for cyanide resistance was a pigment the CO compound of which had its absorption band at a wavelength longer than 580 mmu. In addition, kinetic data suggested that there were two oxidases having different affinities for cyanide. From the data presented, resistance to cyanide in Achromobacter strain D was attributed to the induced formation of cytochrome a(2), which has a very low affinity for cyanide. Several characteristics of cytochrome a(2) as a cytochrome oxidase are summarized.
冈田哲夫（日本东京大学）和有马圭。无色杆菌中的氰化物抗性。II. 氰化物抗性机制。《细菌学杂志》90:744 - 747。1965年。 - 光化学数据表明，在无色杆菌对氰化物敏感的细胞中发现的唯一氧化酶是细胞色素o，而抗氰化物的细胞至少含有两种氧化酶。负责氰化物抗性的氧化酶是一种色素，其一氧化碳化合物的吸收带在波长大于580毫微米处。此外，动力学数据表明存在两种对氰化物亲和力不同的氧化酶。根据所提供的数据，无色杆菌菌株D对氰化物的抗性归因于细胞色素a(2)的诱导形成，细胞色素a(2)对氰化物的亲和力非常低。总结了细胞色素a(2)作为细胞色素氧化酶的几个特性。
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