Iwao Keiichiro, Kobayashi Hiroshi, Okinami Satoshi
Department of Ophthalmology, Faculty of Medicine, Saga University, Japan.
Nippon Ganka Gakkai Zasshi. 2006 Mar;110(3):193-8.
To report the cause and magnetic resonance imaging (MRI) findings in a case of abducent palsy following herpes zoster ophthalmicus.
A 76-year-old man presented with acute onset of pain, a vesicular cutaneous eruption and herpes zoster ophthalmicus on the right side. He developed complete abducent palsy on the right side two weeks after onset. MRI with gadolinium enhancement showed Meckel's sinus, which contains the trigeminal ganglion, and the abducent nerve on the right side. The patient was treated with intravenous acyclovir and methylprednisolone. The abnormal enhancement shown on MRI vanished immediately and the ophthalmoplegia resolved significantly.
This is the first reported case where an affected cranial nerve was detected next to the inflammatory cavernous sinus in ophthalmoplegia following herpes zoster ophthalmicus. These MRI findings showed that this ophthlamoplegia was induced by direct viral invasion or extension of inflammation to the ipsilateral cranial nerve. Further studies need to be performed to clarify the role of specific antiviral therapy or anti-inflammatory agents in treating this complication of herpes zoster.
报告1例眼带状疱疹后展神经麻痹的病因及磁共振成像(MRI)表现。
一名76岁男性,右侧突发疼痛、水疱性皮肤疹及眼带状疱疹。发病两周后出现右侧完全性展神经麻痹。钆增强MRI显示包含三叉神经节的 Meckel 腔及右侧展神经。患者接受静脉注射阿昔洛韦和甲泼尼龙治疗。MRI显示的异常强化立即消失,眼肌麻痹明显缓解。
这是首次报道在眼带状疱疹后眼肌麻痹中,在炎性海绵窦旁检测到受累颅神经的病例。这些MRI表现表明,这种眼肌麻痹是由病毒直接侵袭或炎症蔓延至同侧颅神经所致。需要进一步研究以阐明特定抗病毒治疗或抗炎药物在治疗带状疱疹这种并发症中的作用。