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非心脏手术患者术前常规心电图的预后价值

Prognostic value of routine preoperative electrocardiography in patients undergoing noncardiac surgery.

作者信息

Noordzij Peter G, Boersma Eric, Bax Jeroen J, Feringa Harm H H, Schreiner Frodo, Schouten Olaf, Kertai Miklos D, Klein Jan, van Urk Hero, Elhendy Abdou, Poldermans Don

机构信息

Department of Anesthesiology, Erasmus Medical Center, Rotterdam, The Netherlands.

出版信息

Am J Cardiol. 2006 Apr 1;97(7):1103-6. doi: 10.1016/j.amjcard.2005.10.058. Epub 2006 Feb 28.

Abstract

Electrocardiography is commonly performed as part of preoperative cardiovascular risk assessment in patients undergoing noncardiac surgery. However, the prognostic value of such electrocardiography is still not clear. This study retrospectively studied 23,036 patients who underwent 28,457 surgical procedures at Erasmus Medical Center from 1991 to 2000. Patients were screened before surgery by type of surgery, cardiovascular risk factors (history of coronary heart disease, heart failure, diabetes mellitus, renal dysfunction, and stroke), and preoperative electrocardiography. Electrocardiographic (ECG) results showing atrial fibrillation, left or right bundle branch block, left ventricular hypertrophy, premature ventricular complexes, pacemaker rhythm, or Q-wave or ST-segment changes were classified as abnormal. Multivariate logistic regression was applied to evaluate the relation between ECG abnormalities and cardiovascular death. In-hospital cardiovascular death was observed in 199 of 28,457 patients (0.7%). Patients with abnormal ECG findings had a greater incidence of cardiovascular death than those with normal ECG results (1.8% vs 0.3%; adjusted odds ratio 4.5, 95% confidence interval 3.3 to 6.0). Adding ECG data to clinical risk factors and the type of surgery resulted in an improved C index for the prediction of cardiovascular death (0.79 vs 0.72). However, in patients who underwent low-risk or low- to intermediate-risk surgery, the absolute difference in the incidence of cardiovascular death between those with and without ECG abnormalities was only 0.5%. In conclusion, preoperative electrocardiography provides prognostic information in addition to clinical characteristics and the type of surgery. However, the usefulness of its routine use in lower risk surgery is questionable.

摘要

心电图检查通常作为非心脏手术患者术前心血管风险评估的一部分。然而,这种心电图检查的预后价值仍不明确。本研究回顾性分析了1991年至2000年在伊拉斯姆斯医学中心接受28457例外科手术的23036例患者。术前根据手术类型、心血管危险因素(冠心病史、心力衰竭、糖尿病、肾功能不全和中风)以及术前心电图对患者进行筛查。心电图(ECG)结果显示房颤、左或右束支传导阻滞、左心室肥厚、室性早搏、起搏器节律或Q波或ST段改变均被分类为异常。采用多因素logistic回归分析评估心电图异常与心血管死亡之间的关系。28457例患者中有199例(0.7%)发生院内心血管死亡。心电图结果异常的患者心血管死亡发生率高于心电图结果正常的患者(1.8%对0.3%;调整后的优势比为4.5,95%置信区间为3.3至6.0)。将心电图数据添加到临床危险因素和手术类型中,可提高预测心血管死亡的C指数(0.79对0.72)。然而,在接受低风险或低至中等风险手术的患者中,心电图异常与正常患者的心血管死亡发生率绝对差异仅为0.5%。总之,术前心电图检查除了提供临床特征和手术类型外,还能提供预后信息。然而,在低风险手术中常规使用心电图的实用性值得怀疑。

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