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全膝关节置换术中的失血:危险因素分析

Blood loss in total knee arthroplasty: an analysis of risk factors.

作者信息

Prasad Narayana, Padmanabhan Vinod, Mullaji Arun

机构信息

Trauma and Orthopaedics, Bombay Hospital and Postgraduate Institute, Mumbai, India.

出版信息

Int Orthop. 2007 Feb;31(1):39-44. doi: 10.1007/s00264-006-0096-9. Epub 2006 Mar 28.

Abstract

The amount of blood loss in a primary cemented total knee arthroplasty (TKA) seems to vary in different reported studies. We carried out a prospective study to determine the factors affecting the peri-operative blood loss, hidden blood loss and blood transfusion requirements in a primary cemented total knee arthroplasty. The factors analysed were gender, diagnosis, tourniquet time and body mass index (BMI). We included a total of 66 consecutive patients who underwent primary TKA by a single surgeon (A.M). There was significantly more peri-operative blood loss in male patients than in females (p=0.001, Student's t test). The patients with rheumatoid arthritis did not show any statistical difference in peri-operative blood loss compared with that in patients with osteoarthritis. The tourniquet time and the surgical time showed a positive correlation with peri-operative blood loss. The BMI did not show any correlation with peri-operative blood loss. The incidence of blood transfusion was significantly higher in patients with rheumatoid knees as their pre-operative haemoglobin value was low. The amount of hidden blood loss in our series was 38%. We concluded that gender and tourniquet time plays a role in blood loss in TKA, but diagnosis (advanced osteoarthritis [OA] or rheumatoid arthritis (RA) does not. The blood transfusion depends on both pre-operative haemoglobin value and intra-operative blood loss. The post-operative transfusion trigger can be brought to 8.0 g% in a haemodynamically stable patient.

摘要

在不同的报道研究中,初次骨水泥型全膝关节置换术(TKA)的失血量似乎有所不同。我们进行了一项前瞻性研究,以确定影响初次骨水泥型全膝关节置换术中围手术期失血量、隐性失血量和输血需求的因素。分析的因素包括性别、诊断、止血带使用时间和体重指数(BMI)。我们纳入了总共66例由单一外科医生(A.M.)进行初次TKA的连续患者。男性患者的围手术期失血量明显多于女性患者(p = 0.001,学生t检验)。类风湿性关节炎患者与骨关节炎患者相比,围手术期失血量无统计学差异。止血带使用时间和手术时间与围手术期失血量呈正相关。BMI与围手术期失血量无相关性。类风湿性膝关节患者的输血发生率明显较高,因为他们术前血红蛋白值较低。我们系列中的隐性失血量为38%。我们得出结论,性别和止血带使用时间在TKA失血量中起作用,但诊断(晚期骨关节炎[OA]或类风湿性关节炎[RA])不起作用。输血取决于术前血红蛋白值和术中失血量。对于血流动力学稳定的患者,术后输血触发值可降至8.0 g%。

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