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2004年芝加哥和洛杉矶县健康新生儿社区获得性耐甲氧西林金黄色葡萄球菌感染

Community-associated methicillin-resistant Staphylococcus aureus infection among healthy newborns--Chicago and Los Angeles County, 2004.

出版信息

MMWR Morb Mortal Wkly Rep. 2006 Mar 31;55(12):329-32.

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) infection has long been associated with exposure in health-care settings but emerged in the late 1990s among previously healthy adults and children in the community. Community-associated MRSA (CA-MRSA) infections most commonly are skin and soft-tissue infections; however, certain cases can progress to invasive tissue infections, bacteremia, and death. This report describes two independent investigations by local health departments, assisted by CDC, into outbreaks of MRSA skin infection among otherwise healthy, full-term newborns delivered at hospitals in Chicago, Illinois, and Los Angeles County, California. In both locations, MRSA transmission likely occurred in the newborn nursery; however, laboratory testing identified the MRSA strain as one that was described initially in association with CA-MRSA infections and outbreaks and that differs from predominant health-care-associated MRSA (HA-MRSA) strains. The findings from these investigations underscore 1) the need for health-care providers to be aware that MRSA can cause skin infections among otherwise healthy newborns and 2) the importance of adhering to standard infection-control practices, including consistent hand hygiene, in newborn nurseries.

摘要

耐甲氧西林金黄色葡萄球菌(MRSA)感染长期以来一直与在医疗环境中的接触有关,但在20世纪90年代末出现在社区中原本健康的成人和儿童中。社区获得性MRSA(CA-MRSA)感染最常见的是皮肤和软组织感染;然而,某些病例可能进展为侵袭性组织感染、菌血症和死亡。本报告描述了当地卫生部门在疾病控制和预防中心(CDC)协助下,对伊利诺伊州芝加哥市和加利福尼亚州洛杉矶县医院出生的健康足月新生儿中MRSA皮肤感染暴发进行的两项独立调查。在这两个地点,MRSA传播可能发生在新生儿病房;然而,实验室检测确定该MRSA菌株是最初与CA-MRSA感染和暴发相关的菌株,且与主要的医疗保健相关MRSA(HA-MRSA)菌株不同。这些调查结果强调了1)医疗保健提供者需要意识到MRSA可在原本健康的新生儿中引起皮肤感染,以及2)在新生儿病房坚持标准感染控制措施(包括持续手部卫生)的重要性。

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