Nichols Catherine M, Nam Marie, Ramakrishnan Viswanathan, Lamb Elizabeth H, Currie Nancy
Department of Obstetrics and Gynecology, Medical College of Virginia, Virginia Commonwealth University Medical Center, Richmond, VA, USA.
Am J Obstet Gynecol. 2006 May;194(5):1450-4. doi: 10.1016/j.ajog.2006.01.059. Epub 2006 Mar 31.
The purpose of this study was to determine the rate of new bowel symptoms and anal sphincter defects in primiparous women with and without recognized anal sphincter (AS) injury.
One hundred seventeen primiparous women classified with increasing degrees of perineal trauma and 21 controls delivered by cesarean section were enrolled immediately postpartum and demographic and delivery data were collected. At 6 weeks' postpartum, subjects completed a bowel function questionnaire and endoanal ultrasonography was performed. Logistic regression, chi-square, and 2-sample t tests were used for statistical analysis.
A significant difference in new bowel symptoms was reported in women with (39%) and without (11%) recognized AS injury (P = .002). AS defects were present in 0%, 15%, 23%, 37%, and 67% of women with C/S, first-, second-, third-, and fourth-degree lacerations, respectively. Combined defects of the internal and external AS were associated with the greatest risk of new bowel symptoms (OR 32.1 [95% CI 9.6-107], P < .001).
In women with and without recognized AS trauma, new bowel symptoms were strongly correlated with the presence of anatomic AS defects postpartum.
本研究旨在确定有无确诊肛门括约肌(AS)损伤的初产妇中新发肠道症状及肛门括约肌缺陷的发生率。
117例根据会阴创伤程度递增分类的初产妇及21例剖宫产分娩的对照组产妇在产后立即纳入研究,并收集人口统计学和分娩数据。产后6周时,受试者完成一份肠道功能问卷并接受肛管超声检查。采用逻辑回归、卡方检验和双样本t检验进行统计分析。
有确诊AS损伤的女性(39%)和无确诊AS损伤的女性(11%)新发肠道症状存在显著差异(P = 0.002)。分别有0%、15%、23%、37%和67%的剖宫产、一度、二度、三度和四度裂伤的女性存在AS缺陷。AS内外联合缺陷与新发肠道症状的风险最高相关(比值比32.1 [95%置信区间9.6 - 107],P < 0.001)。
无论有无确诊AS创伤,初产妇产后新发肠道症状与解剖学AS缺陷的存在密切相关。