Trück J
Medizinische Universitätskinderklinik Bern, Inselspital, Bern.
Praxis (Bern 1994). 2006 Mar 29;95(13):501-4. doi: 10.1024/0369-8394.95.13.501.
A four-month-old infant was hospitalized because of RSV bronchiolitis. Two days after presentation he developed rhabdomyolysis, most probably as a result of multiple factors (hyperthermia, hypovolemia/dehydration, hypernatremia, metabolic acidosis), followed by severe complications including acute renal failure, hepatic dysfunction and disseminated intravascular coagulation. Under sufficient fluid supply he recovered completely. In rhabdomyolysis clinical symptoms vary. Seldom, the classical trial of muscle pain, weakness, and dark urine is observed. Severe complications are hypovolemia, electrolyte disorders, a compartment syndrome, disseminated intravascular coagulation and acute renal failure, which causes death in 20% of the patients, although non-traumatic causes seem to have better outcome. The mainly therapeutic option is to correct the hypovolemia with sufficient fluid supply.
一名四个月大的婴儿因呼吸道合胞病毒细支气管炎住院。就诊两天后,他出现了横纹肌溶解症,很可能是多种因素(高热、血容量不足/脱水、高钠血症、代谢性酸中毒)导致的,随后出现了严重并发症,包括急性肾衰竭、肝功能障碍和弥散性血管内凝血。在充足的液体供应下,他完全康复了。横纹肌溶解症的临床症状各不相同。很少会出现典型的肌肉疼痛、无力和深色尿液症状。严重并发症包括血容量不足、电解质紊乱、骨筋膜室综合征、弥散性血管内凝血和急性肾衰竭,20%的患者会因此死亡,不过非创伤性病因的预后似乎较好。主要的治疗选择是通过充足的液体供应来纠正血容量不足。