Swennen Q, Janssens G P J, Collin A, Le Bihan-Duval E, Verbeke K, Decuypere E, Buyse J
Laboratory for Livestock Physiology and Immunology, Department of Biosystems, Katholieke Universiteit Leuven, Kasteelpark Arenberg 30, 3001 Leuven, Belgium.
Poult Sci. 2006 Apr;85(4):731-42. doi: 10.1093/ps/85.4.731.
The main objectives of this study were to explore the role of diet-induced thermogenesis in the regulation of voluntary feed intake and to determine the glucose oxidation of broiler chicken strains, known to differ in glucose-insulin balance. From 2 to 7 wk of age, male broiler chickens of a fat and a lean line were reared on 1 of 2 isoenergetic diets with constant gross energy and carbohydrate levels but with substitutions between fat and protein. The low protein (LP/HF) diet contained 126 g of protein/kg and 106 g of fat/kg, whereas the low fat (LF/HP) diet contained 242 g of protein/kg and 43 g of fat/kg. There was no significant effect of the genetic background of the broilers on the glucose oxidation rate (as measured by stable isotope breath test) or protein oxidation (as measured by plasma uric acid levels). Considering the difference in carcass composition (fat content) of both lines, this leads to the hypothesis that the lines differ predominantly in fat metabolism. Although there was no line effect on plasma triglyceride and free fatty acid concentrations, it was hypothesized that there might be differences in fat oxidation or de novo lipogenesis, or both, between the genotypes. Diet-induced thermogenesis per metabolic body weight (kg of BW0.75) per 24 h, expressed per gram of feed intake, was not significantly influenced by genetic background or by diet composition. Therefore, a model linking feed intake to diet-induced thermogenesis, as postulated for adult mammals, could not be corroborated for growing broiler chickens.
本研究的主要目的是探讨饮食诱导产热在调节自愿采食量中的作用，并确定已知在葡萄糖 - 胰岛素平衡方面存在差异的肉鸡品系的葡萄糖氧化情况。从2周龄到7周龄，将一个肥胖品系和一个瘦肉品系的雄性肉鸡饲养在两种等能量日粮中的一种上，这两种日粮的总能和碳水化合物水平恒定，但脂肪和蛋白质之间相互替代。低蛋白（LP/HF）日粮每千克含有126克蛋白质和106克脂肪，而低脂（LF/HP）日粮每千克含有242克蛋白质和43克脂肪。肉鸡的遗传背景对葡萄糖氧化率（通过稳定同位素呼吸试验测量）或蛋白质氧化（通过血浆尿酸水平测量）没有显著影响。考虑到两个品系在胴体组成（脂肪含量）上的差异，这导致了一个假设，即两个品系在脂肪代谢方面存在主要差异。虽然品系对血浆甘油三酯和游离脂肪酸浓度没有影响，但据推测，不同基因型之间在脂肪氧化或从头脂肪生成，或两者方面可能存在差异。每24小时每代谢体重（千克体重的0.75次方）的饮食诱导产热，以每克采食量表示，不受遗传背景或日粮组成的显著影响。因此，对于生长中的肉鸡，无法证实像成年哺乳动物那样将采食量与饮食诱导产热联系起来的模型。
