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[耳鼻喉科领域的淀粉样变性]

[Amyloidosis in the ORL field].

作者信息

Vázquez de la Iglesia F, Sánchez Ferrándis N, Rey Martínez J, Ruba San Miguel D, Rama López J, Fernández González S

机构信息

Hospital Ntra. Sra. de Belén, La Coruña.

出版信息

Acta Otorrinolaringol Esp. 2006 Mar;57(3):145-8. doi: 10.1016/s0001-6519(06)78680-0.

Abstract

OBJECTIVES

To review the clinical and pathological characteristics of upper aerodigestive tract amyloidosis with particular attention to laryngeal amyloidosis. Amyloidosis of the upper aerodigestive tract is relatively rare. The larynx is the most common site of involvement in head and neck isolated amyloidosis and the supraglottic region represents the major site of involvement.

MATERIAL AND METHODS

Retrospective review of 6 patients diagnosed with upper aerodigestive tract amyloidosis. Hoarseness and airway compromise were the main presenting symptoms.

RESULTS

Laryngeal CO2 laser microsurgery was performed and then we refered the patients to the Medical Deparment seeking for systemic involvement and ENT Clinic follow up.

CONCLUSIONS

In our experience, laryngeal CO2 laser microsurgery is a succesfull way to treat isolated laryngeal amyloidosis with clinical improvement and low recurrence rates.

摘要

目的

回顾上呼吸道消化道淀粉样变性的临床和病理特征,尤其关注喉淀粉样变性。上呼吸道消化道淀粉样变性相对少见。喉部是头颈部孤立性淀粉样变性最常累及的部位,声门上区是主要受累部位。

材料与方法

对6例诊断为上呼吸道消化道淀粉样变性的患者进行回顾性研究。主要症状为声音嘶哑和气道受压。

结果

进行了喉部二氧化碳激光显微手术,然后将患者转至内科以寻找全身受累情况,并在内科门诊进行随访。

结论

根据我们的经验,喉部二氧化碳激光显微手术是治疗孤立性喉淀粉样变性的成功方法,临床症状改善且复发率低。

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