Wang Le-feng, Xu Li, Yang Xin-chun, Ge Yong-gui, Wang Hong-shi, Tong Zi-chuan, Zou Yang-chun, Xue Wei-zhen, Li Wei-ming
Heart Center, Beijing Chaoyang Hospital, Institute of Cardiovascular Diseases, Capital University of Medical Science, Beijing 100020, China.
Zhonghua Xin Xue Guan Bing Za Zhi. 2006 Jan;34(1):5-7.
The effects of primary percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) induced by left main (LM) artery occlusion were analyzed retrospectively in this study.
A total of 1343 consecutive AMI patients who underwent primary PCI between January 1995 and December 2004 were retrospectively studied.
LM occlusion or severe stenosis were found in 11 patients [all male, mean age (56.4 +/- 9.2) years (range 43-70 years)], cardiogenic shock was overt in 6 patients. Primary PCI were performed under the assistance of intra-aortic balloon pump (IABP) in these patients [8 stent implantation, 3 balloon dilation and 2 necessitating emergency CABG after balloon dilation]. In-hospital mortality was 45.5% (5/11). Three-month follow-up were made in all survivals (6/11). Analysis showed good collateral circulation flow from right coronary artery to left coronary artery was existed in all survival cases before PCI.
Prognosis of AMI patients with LM artery obstruction or severe stenosis was poor. Patients with pre-existed collateral circulation before primary PCI and IABP had a better clinical outcomes.
本研究回顾性分析了经皮冠状动脉介入治疗(PCI)对左主干(LM)动脉闭塞所致急性心肌梗死(AMI)患者的疗效。
回顾性研究了1995年1月至2004年12月期间连续接受初次PCI的1343例AMI患者。
11例患者(均为男性,平均年龄[56.4±9.2]岁,范围43 - 70岁)发现有LM闭塞或严重狭窄,6例出现心源性休克。这些患者在主动脉内球囊反搏(IABP)辅助下进行了初次PCI[8例植入支架,3例球囊扩张,2例球囊扩张后需紧急冠状动脉旁路移植术(CABG)]。院内死亡率为45.5%(5/11)。对所有存活患者(6/11)进行了3个月的随访。分析显示,所有存活病例在PCI前均存在从右冠状动脉到左冠状动脉的良好侧支循环血流。
LM动脉阻塞或严重狭窄的AMI患者预后较差。初次PCI和IABP前存在侧支循环的患者临床结局较好。