Fröhlig Gerd, Gras Daniel, Victor Jacques, Mabo Philippe, Galley Daniel, Savouré Arnaud, Jauvert Gaël, Defaye Pascal, Ducloux Pascale, Amblard Amel
Medizinische Universitatsklinik III, Universitätskliniken des Saarlandes Innere Medizin III, Homburg Germany.
Europace. 2006 Feb;8(2):96-101. doi: 10.1093/europace/euj024. Epub 2006 Jan 9.
To examine the performance of AAIsafeR2, a new pacing mode to minimize the cumulative proportion of ventricular pacing in patients who do not need regular ventricular support.
The safety of AAIsafeR2 was examined in 123 recipients (73 +/- 12 years old, 51% men) of dual chamber pacemakers implanted for sinus node dysfunction, paroxysmal AV block or the bradycardia-tachycardia syndrome. Data were collected from pacemaker diagnostics, and the first 43 patients underwent 24-h Holter recordings before being discharged from the hospital with AAIsafeR2 activated. No adverse event related to AAIsafeR2 was observed. All ventricular pauses detected on Holter tapes triggered immediate back-up ventricular pacing. Appropriate switches to DDD occurred in 97 of 123 patients. In 69 of 123 devices (56%) switches to DDD were non-sustained, and the average % ventricular pacing in this group was 0.2+/-0.5%.
AAIsafeR2 mode seems to be safe and reliable in patients with infrequent slowing or pauses in ventricular activity, while maintaining ventricular pacing below 1%.
研究AAIsafeR2这种新的起搏模式在不需要常规心室支持的患者中使心室起搏累积比例最小化的性能。
对123例因窦房结功能障碍、阵发性房室传导阻滞或心动过缓-心动过速综合征植入双腔起搏器的患者（73±12岁，51%为男性）进行了AAIsafeR2安全性研究。数据从起搏器诊断中收集，前43例患者在激活AAIsafeR2出院前接受了24小时动态心电图记录。未观察到与AAIsafeR2相关的不良事件。动态心电图记录上检测到的所有心室停搏均触发了立即备用心室起搏。123例患者中有97例适时转换为DDD模式。123台设备中有69台（56%）转换为DDD模式是短暂的，该组心室起搏平均百分比为0.2±0.5%。
AAIsafeR2模式在心室活动偶尔减慢或停搏的患者中似乎安全可靠，同时能将心室起搏维持在1%以下。
