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这位新型心脏手术患者:突破以往预期。

The new cardiac surgery patient: defying previous expectations.

作者信息

Aggarwal Sandeep K, Fox Stephanie A, Stitt Larry, Kiaii Bob, McKenzie F Neil, Menkis Alan H, Quantz Mackenzie A, Novick Richard J

机构信息

Schulich School of Medicine and Dentistry, University of Western Ontario, London Health Sciences Centre, London, ON.

出版信息

Can J Surg. 2006 Apr;49(2):117-22.

Abstract

BACKGROUND

Studies conducted before 1999 of patients who had coronary artery bypass graft surgery (CABG) have shown a tendency toward increasing preoperative risk factors. This study examines whether this trend of increasing risk in patients who have cardiac surgery has continued since 1999 and whether its effect on mortality and morbidity has changed.

METHODS

We prospectively collected data for 2754 patients who had cardiac surgery, divided them into 4 cohorts based on the year of operation (2000-2003) and analyzed the data according to 56 predefined preoperative, operative and postoperative variables.

RESULTS

There were no significant changes in most preoperative risk factors over time, except for significant decreases in the proportion of elective (p = 0.016) and emergency/salvage operations (p < 0.001) and increases in urgent procedures and in the number of patients with congestive heart failure (CHF) (p < 0.001). The proportion of CABG procedures decreased significantly, whereas the proportion of valve, CABG plus valve, and non-CABG surgeries increased. A significant increase in multiarterial graft use and a decrease in off-pump coronary artery bypass procedures were observed. Postoperative complication rates did not change during the 4 years except for a significant decrease in wound infections. No significant changes in overall mortality and mortality across types of procedure were observed. Median observed/expected ratios for expected length of stay in hospital and risk of mortality did not change significantly over time.

CONCLUSION

Patients' risk factors, except for CHF, did not change from 2000 to 2003. Despite more complicated procedures, the postoperative complication rates did not change except for a decrease in wound infections. These results suggest that the assumption of an inexorably increasing patient risk profile should be re-evaluated.

摘要

背景

1999年以前对接受冠状动脉搭桥手术(CABG)患者进行的研究显示,术前危险因素有增加的趋势。本研究旨在探讨自1999年以来,心脏手术患者这种风险增加的趋势是否持续,以及其对死亡率和发病率的影响是否发生了变化。

方法

我们前瞻性收集了2754例接受心脏手术患者的数据,根据手术年份(2000 - 2003年)将他们分为4组,并根据56个预先定义的术前、术中和术后变量对数据进行分析。

结果

随着时间的推移,大多数术前危险因素没有显著变化,但择期手术(p = 0.016)和急诊/挽救手术的比例显著下降(p < 0.001),紧急手术的比例以及充血性心力衰竭(CHF)患者的数量增加(p < 0.001)。冠状动脉搭桥手术的比例显著下降,而瓣膜手术、冠状动脉搭桥加瓣膜手术和非冠状动脉搭桥手术的比例增加。观察到多支动脉移植的使用显著增加,非体外循环冠状动脉搭桥手术的比例下降。除伤口感染显著减少外,4年间术后并发症发生率没有变化。总体死亡率和各类手术的死亡率没有显著变化。观察到的住院预期时间中位数/预期比值和死亡风险随时间没有显著变化。

结论

2000年至2003年,除CHF外,患者的危险因素没有变化。尽管手术更加复杂,但除伤口感染减少外,术后并发症发生率没有变化。这些结果表明,应重新评估患者风险状况必然增加的假设。

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