Seshadri L, Oomman M, Hemalatha K, Jairaj P
Department of Obstetrics and Gynaecology, Christian Medical College, Hospital, Vellore, India.
Indian J Cancer. 1991 Mar;28(1):27-32.
Evidence of human papilloma virus (HPV) infection was sought in 50 patients with cervical intraepithelial neoplasia (CIN) and 50 controls. Cytologic, colposcopic and histopathological examinations were carried out in each one of them. Cytological evidence of HPV infection was found in 13 cases and two controls. Colposcopic evidence was found in 33 (66%) cases and 17 (34%) controls and histopathological evidence in 35 (70%) patients and 14 (28%) controls. These differences were statistically significant. Colposcopy proved to be a good method of diagnosing HPV infection with a sensitivity of 86% and specificity of 80% compared to histopathologic diagnosis.
在50例宫颈上皮内瘤变（CIN）患者和50例对照中寻找人乳头瘤病毒（HPV）感染的证据。对每组中的每个人都进行了细胞学、阴道镜检查和组织病理学检查。在13例病例和2例对照中发现了HPV感染的细胞学证据。在33例（66%）病例和17例（34%）对照中发现了阴道镜证据，在35例（70%）患者和14例（28%）对照中发现了组织病理学证据。这些差异具有统计学意义。与组织病理学诊断相比，阴道镜检查被证明是诊断HPV感染的一种好方法，其敏感性为86%，特异性为80%。
