进展期前列腺癌：泌尿外科医生的治疗选择

Advancing prostate cancer: treatment options for the urologist.

作者信息

Lowrance William T, Chang Sam S

机构信息

Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232-2765, USA.

出版信息

Urol Clin North Am. 2006 May;33(2):211-7, vii. doi: 10.1016/j.ucl.2005.12.003.

DOI:10.1016/j.ucl.2005.12.003

PMID:16631459

Abstract

Today's urologists often face the dilemma of how to treat patients who have advancing prostate cancer. The diversity of this patient population makes treatment decisions challenging. For over 60 years the mainstay of treatment for patients who have advancing prostate cancer has been androgen deprivation therapy. Now there are new chemotherapeutic options, novel hormone manipulations, and other adjunctive therapies available. Based on a case presentation, the authors have attempted to outline for the practicing urologist, a logical progression of treatment options for advancing prostate cancer.

摘要

如今，泌尿外科医生常常面临如何治疗前列腺癌进展期患者的两难困境。这类患者群体的多样性使得治疗决策颇具挑战性。60多年来，前列腺癌进展期患者的主要治疗方法一直是雄激素剥夺疗法。现在有了新的化疗方案、新型激素调控方法以及其他辅助治疗手段。基于一个病例介绍，作者试图为泌尿外科执业医生勾勒出前列腺癌进展期治疗方案的合理递进过程。