Tsutsumi Yutaka, Kanamori Hiroe, Tanaka Junji, Asaka Masahiro, Imamura Masahiro, Masauzi Nobuo
Department of Internal Medicine, Hakodate Municipal Hospital, Hakodate, Japan.
Pain Med. 2006 Mar-Apr;7(2):164-5. doi: 10.1111/j.1526-4637.2006.00107.x.
A 47-year-old woman who underwent allogenic peripheral blood stem cell transplant developed withdrawal symptoms soon after Fentanyl 25 mcg/h patch was stopped, which has not been reported at this dose. Possible causes, such as the inhibition of CYP3A4 induced by cyclosporine causing elevations of serum fentanyl, are discussed.