Coury Ch, Lellouch A, Bientz M, Diebold J, Camilleri J P, Reynes M
Sem Hop. 1975 Jan 14;51(3):169-76.
The authors report 79 needle biopsies of the liver, using a Menghini needle, carried out as routine in untreated cases of pulmonary tuberculosis with positive sputum. Apart from the histological study, the authors carried out, in 30 cases, a bacteriological study of the liver fragment. The bacteriological and histological results are reported here in detail, then compared with those in the world literature. No significant correlation was found between the histological type of the suggestive hepatic lesions, e.g. follicular appearances or appearances of nodular küpferian hyperplasia and the radioclinical variety of pulmonary tuberculosis, e.g. parenchymatous, pleural or miliary. The authors emphasize the significance of each type of pathological lesion encountered, in particular, the appearance of nodular küpferian hyperplasia or intralobular, lymphohistiocytic islets, which seem to them remarkable by their relative frequency and their chararacter fairly suggestive of tuberculosis. In spite of the low number of pathological appearances obtained in these liver biopsies, the present study nevertheless permitted a few interesting conclusions on the blood spread of the tubercle bacillus and the significance of changes in the Küpfer system during common pulmonary tuberculosis.
作者报告了79例使用Menghini针进行的肝脏穿刺活检,这些活检是在痰菌阳性的未经治疗的肺结核病例中作为常规操作进行的。除了组织学研究外,作者还对30例病例的肝组织碎片进行了细菌学研究。这里详细报告细菌学和组织学结果,然后与世界文献中的结果进行比较。在提示性肝脏病变的组织学类型,如滤泡样表现或结节性库普弗细胞增生的表现,与肺结核的放射临床类型,如实质性、胸膜性或粟粒性之间,未发现显著相关性。作者强调了所遇到的每种病理病变的意义,特别是结节性库普弗细胞增生或小叶内淋巴细胞-组织细胞岛的出现,它们在相对频率和相当提示结核病的特征方面对作者来说似乎很显著。尽管在这些肝脏活检中获得的病理表现数量较少,但本研究仍然对结核杆菌的血行播散以及普通肺结核期间库普弗系统变化的意义得出了一些有趣的结论。