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淋巴瘤样丘疹病:与急性痘疮样苔藓样糠疹的临床病理比较研究

Lymphomatoid papulosis: clinicopathological comparative study with pityriasis lichenoides et varioliformis acuta.

作者信息

Erpaiboon P, Mihara I, Niimura M

机构信息

Department of Dermatology, Jikei University School of Medicine, Tokyo, Japan.

出版信息

J Dermatol. 1991 Oct;18(10):580-5. doi: 10.1111/j.1346-8138.1991.tb03136.x.

DOI:10.1111/j.1346-8138.1991.tb03136.x
PMID:1665158
Abstract

We have compared the clinical and histopathological features of 6 patients with lymphomatoid papulosis (LP) and 14 patients with pityriasis lichenoides et varioliformis acuta (PLEVA). There were some differences between the clinical features in the two diseases, including the size and appearance of skin lesions and the duration of the course of disease. Ki-1 Ag positive, large, atypical, lymphoid cells were always seen in lymphomatoid papulosis; none of lymphoid cells of pityriasis lichenoides et varioliformis acuta demonstrated this antigen. We conclude that lymphomatoid papulosis and PLEVA, although sharing some common features, should be considered to be different clinical and immunopathological entities.

摘要

我们比较了6例淋巴瘤样丘疹病(LP)患者和14例急性痘疮样苔藓样糠疹(PLEVA)患者的临床和组织病理学特征。这两种疾病的临床特征存在一些差异,包括皮肤损害的大小和外观以及病程持续时间。淋巴瘤样丘疹病中总能见到Ki-1抗原阳性的大的非典型淋巴细胞;急性痘疮样苔藓样糠疹的淋巴细胞均未显示该抗原。我们得出结论,淋巴瘤样丘疹病和急性痘疮样苔藓样糠疹虽然有一些共同特征,但应被视为不同的临床和免疫病理学实体。

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