Sakai Yu
Department of Pathology, Japan Self Defense Forces Sapporo General Hospital, 12-1-32 Hiragishi 1 Jo, Toyohira-ku, Sapporo, Hokkaido 062-0931, Japan.
Arch Gynecol Obstet. 2007 Jan;275(1):59-61. doi: 10.1007/s00404-006-0167-6. Epub 2006 May 5.
An unusual case of epithelioid vascular leiomyoma mimicking glomangiomyoma arising in the uterine corpus of a 55-year-old Japanese woman is presented. The surgically resected uterine mass, measuring 4.0x3.5 cm2, demonstrated a dark red well-circumscribed tumor. Histologically, the rounded epithelioid cells around the dilated vessels showed gradual transition to spindled smooth muscle cells. Immunohistochemistry was positive for smooth muscle actin, but negative for collagen IV.
The experience in this case emphasizes that glomangiomyoma-like feature is interesting and might indeed be a new histological variant of uterine leiomyomas.
本文报道了一例罕见的上皮样血管平滑肌瘤,其表现类似血管球瘤,发生于一名55岁日本女性的子宫体部。手术切除的子宫肿物大小为4.0×3.5平方厘米,呈暗红色,边界清晰。组织学检查显示,扩张血管周围的圆形上皮样细胞逐渐过渡为梭形平滑肌细胞。免疫组化结果显示平滑肌肌动蛋白呈阳性,而IV型胶原呈阴性。
该病例的经验强调,类似血管球瘤的特征很有趣,可能确实是子宫平滑肌瘤的一种新的组织学变体。