Ness Jose, Aronow Wilbert S
Department of Medicine, University of Iowa College of Medicine, Iowa City, Iowa, USA.
Am J Cardiol. 2006 May 15;97(10):1427-8. doi: 10.1016/j.amjcard.2005.12.033. Epub 2006 Mar 24.
Atherosclerotic vascular disease (AVD) and osteoporosis or osteopenia are common conditions among postmenopausal women and appear to be linked in a manner that is not fully understood. In a retrospective study that was conducted among 1,000 postmenopausal women who were seen in a general medicine clinic, AVD was more commonly seen among women with osteoporosis (92 of 154, 60%) than among those with osteopenia (63 of 179, 35%, p <0.001) or no osteoporosis or osteopenia (148 of 667, 22%, p <0.001). AVD was also more prevalent in women with osteopenia than in those with no osteoporosis or osteopenia (p <0.001). Modifiable risk factors for AVD were present to the same extent in women with osteoporosis, osteopenia, or no osteoporosis or osteopenia.
动脉粥样硬化性血管疾病(AVD)和骨质疏松症或骨质减少症在绝经后女性中很常见,而且它们之间的关联方式尚未完全明确。在一项针对1000名于普通内科门诊就诊的绝经后女性开展的回顾性研究中,患有骨质疏松症的女性中AVD更为常见(154例中有92例,占60%),高于骨质减少症女性(179例中有63例, 占35%,p<0.001)或无骨质疏松症或骨质减少症的女性(667例中有148例,占22%,p<0.001)。AVD在骨质减少症女性中也比在无骨质疏松症或骨质减少症的女性中更普遍(p<0.001)。AVD的可改变风险因素在患有骨质疏松症、骨质减少症或无骨质疏松症或骨质减少症的女性中出现的程度相同。