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泰国青光眼患者行透明角膜超声乳化术后的长期眼压变化

Long-term intraocular pressure change after clear corneal phacoemulsification in Thai glaucoma patients.

作者信息

Leelachaikul Yupin, Euswas Ataya

机构信息

Department of Ophthalmology, Faculty of Medicine, Ramathiodi Hospital, Mahidol University, Bangkok 10400, Thailand.

出版信息

J Med Assoc Thai. 2005 Nov;88 Suppl 9:S21-5.

Abstract

OBJECTIVES

To evaluate long-term intraocular pressure (IOP) changes after sutureless clear corneal phacoemulsification in eyes with preoperatively controlled glaucoma.

DESIGN

Retrospective study.

SETTING

Eye Clinic, Ramathibodi Hospital, Faculty of Medicine, Mahidol University.

MATERIAL AND METHOD

The medical records of 218 patients who had uneventful sutureless clear corneal phacoemulsification with acrylic foldable lens (IOL) implantation were retrospectively reviewed. Included were 58 patients with medically controlled open-angle glaucoma and 160 normal controls. Follow-up was 12 to 18 months. Outcome measures were postoperative IOP and number of glaucoma medications.

RESULTS

Postoperatively, there was an insignificant decrease in IOP in the glaucoma group; the mean decrease was 1.4 mm Hg +/- 3.8 (SD) at 12 months and 1.6 +/- 4.2 mm Hg at 18 months. The mean number of medications decreased significantly at 12 months (0.51 +/- 0.75) and at 18 months (0.41 +/- 0.83) (P = .04). The control group also had a significant decrease in IOP, with a mean decrease of 0.83 +/- 2.8 mm Hg at 12 months (P = .01) and 1.26 +/- 2.9 mm Hg at 18 months (P < .0001). The decrease in IOP was more pronounced in eyes with a higher preoperative IOP in both the glaucoma and control groups.

CONCLUSION

These findings suggest that sutureless clear corneal phacoemulsification with foldable acrylic IOL implantation is a relatively safe and simple surgical option in patients with cataract and well-controlled glaucoma. The approach provided favorable long-term IOP change and led to rapid visual rehabilitation in both the glaucoma and control group.

摘要

目的

评估术前眼压得到控制的青光眼患者行无缝线透明角膜超声乳化术后的长期眼压变化。

设计

回顾性研究。

地点

玛希隆大学医学院拉玛提波迪医院眼科诊所。

材料与方法

回顾性分析218例行无缝线透明角膜超声乳化联合丙烯酸可折叠人工晶状体(IOL)植入且手术过程顺利的患者的病历。其中包括58例药物控制的开角型青光眼患者和160例正常对照者。随访时间为12至18个月。观察指标为术后眼压和青光眼药物使用数量。

结果

术后,青光眼组眼压有轻微下降;12个月时平均下降1.4 mmHg±3.8(标准差),18个月时下降1.6±4.2 mmHg。药物平均使用数量在12个月时(0.51±0.75)和18个月时(0.41±0.83)显著减少(P = 0.04)。对照组眼压也有显著下降,12个月时平均下降0.83±2.8 mmHg(P = 0.01),18个月时下降1.26±2.9 mmHg(P < 0.0001)。青光眼组和对照组中,术前眼压较高的眼睛眼压下降更为明显。

结论

这些结果表明,对于白内障合并眼压控制良好的青光眼患者,无缝线透明角膜超声乳化联合可折叠丙烯酸IOL植入是一种相对安全且简单的手术选择。该方法能带来良好的长期眼压变化,并使青光眼组和对照组均能快速恢复视力。

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