内皮素对垂体催乳素细胞的作用：一种受体，多种鸟苷三磷酸结合蛋白。

Endothelin action on pituitary lactotrophs: one receptor, many GTP-binding proteins.

作者信息

Bertram Richard, Tabak Joel, Toporikova Natalia, Freeman Marc E

机构信息

Department of Mathematics, Florida State University, Tallahassee, FL 32306, USA.

出版信息

Sci STKE. 2006 Feb 7;2006(321):er2. doi: 10.1126/stke.3212006er2.

DOI:10.1126/stke.3212006er2

PMID:16685766

Abstract

The endothelins are a family of hormones that have a biphasic action on pituitary lactotrophs. The initial effect is stimulatory, followed later by inhibition that persists long after the agonist has been removed. Recent research has uncovered several G protein pathways that mediate these effects.

摘要

内皮素是一类对垂体催乳细胞具有双相作用的激素。最初的作用是刺激性的，随后是抑制作用，且在激动剂去除后这种抑制作用仍会持续很长时间。最近的研究发现了几种介导这些作用的G蛋白途径。