Wilkinson F, Karanovic O, Ross E C, Lillakas L, Steinbach M J
Department of Psychology, York University, Toronto, ON, Canada.
Cephalalgia. 2006 Jun;26(6):660-71. doi: 10.1111/j.1468-2982.2006.01091.x.
The purpose of this study was to examine basic ocular motor function in individuals with migraine. We used an infrared eye-tracking system to measure horizontal smooth pursuit to a sinusoidal target, saccades to horizontal target displacements of 5-20 degrees , and the stability of fixation in 19 migraine without aura (MoA), 19 migraine with aura (MA) and 19 headache-free control (C) subjects. Eye movement measurements were made at two target displacement rates and against both homogeneous grey and patterned backgrounds. We found no statistically significant differences between migraine and control subjects in any of the eye movement parameters measured, but did find highly significant effects of both target speed and background pattern in all groups. Our results do not provide support for subclinical cerebellar impairment in migraineurs, and do provide evidence that previously described visual abnormalities in migraine are not artefacts of abnormal fixation or eye movements.
本研究的目的是检查偏头痛患者的基本眼动功能。我们使用红外眼动追踪系统，对19名无先兆偏头痛（MoA）患者、19名有先兆偏头痛（MA）患者和19名无头痛对照（C）受试者进行测量，内容包括对正弦波目标的水平平稳跟踪、对5 - 20度水平目标位移的扫视以及注视稳定性。眼动测量在两种目标位移速率下进行，且背景为均匀灰色和图案背景。我们发现，在测量的任何眼动参数方面，偏头痛患者与对照受试者之间均无统计学上的显著差异，但确实发现所有组中目标速度和背景图案均有高度显著影响。我们的结果不支持偏头痛患者存在亚临床小脑损伤，且确实提供了证据表明先前描述的偏头痛视觉异常并非异常注视或眼动的假象。
