食物不耐受与经治疗和未经治疗的肠易激综合征中的皮肤点刺试验
Food intolerance and skin prick test in treated and untreated irritable bowel syndrome.
作者信息
Jun Dae-Won, Lee Oh-Young, Yoon Ho-Joo, Lee Seok-Hwa, Lee Hang-Lak, Choi Ho-Soon, Yoon Byung-Chul, Lee Min-Ho, Lee Dong-Hoo, Cho Sang-Hoen
机构信息
Department of Internal Medicine, College of Medicine, Hanyang University Hospital, Seoul, South Korea 17 Haengdang-dong, Sungdong-ku, Seoul 133-791, Korea.
出版信息
World J Gastroenterol. 2006 Apr 21;12(15):2382-7. doi: 10.3748/wjg.v12.i15.2382.
AIM
To correlate the clinical features of treated and untreated patients with irritable bowel syndrome (IBS) to the results of skin prick test (SPT) for food and inhalant allergens.
METHODS
We recruited 105 subjects to form three different target groups: treated group (n=44) undergoing treatment for IBS, untreated group (n=31) meeting the Rome II criteria without treatment for IBS, control group (n=30) with no IBS symptoms.
RESULTS
SPT results were different among the three groups in which SPT was positive in 17 (38.6%) treated patients, in 5 (16.1%) untreated patients and in 1 (3.3%) control (P<0.01). The number of positive SPTs was greater in the IBS group than in the control group (P<0.001). The number of positive food SPTs was higher in the treated IBS group than in the untreated IBS group (P=0.03).
CONCLUSION
Positive food SPT is higher in IBS patients than in controls.
目的
将接受治疗和未接受治疗的肠易激综合征（IBS）患者的临床特征与食物和吸入性过敏原皮肤点刺试验（SPT）结果进行关联。
方法
我们招募了105名受试者，组成三个不同的目标组：接受IBS治疗的治疗组（n = 44）、符合罗马II标准但未接受IBS治疗的未治疗组（n = 31）、无IBS症状的对照组（n = 30）。
结果
三组的SPT结果不同，其中17名（38.6%）治疗患者、5名（16.1%）未治疗患者和1名（3.3%）对照者的SPT呈阳性（P<0.01）。IBS组的阳性SPT数量多于对照组（P<0.001）。治疗的IBS组中食物SPT阳性数量高于未治疗的IBS组（P = 0.03）。
结论
IBS患者的食物SPT阳性率高于对照组。
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