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CT和核磁共振成像在脊索瘤诊断中的价值。

Value of CT and NMR imaging in diagnosing of chordomas.

作者信息

Woźnica J, Kendall B, Bryc S, Losicki M, Kingsley D

机构信息

Zakład Neuroradiologii i Rentgenodiagnostyki, Instytut Radiologii, Akademia Medyczna w Lublinie.

出版信息

Ann Univ Mariae Curie Sklodowska Med. 1990;45:181-6.

PMID:1670023
Abstract

Chordomas usually occur in the axial skeleton and they arise from the remnants of notochord. Their growth is slow and they often give metastases. Such cases are mainly observed among people above 40 years of age. Most frequently chordomas are situated in sacral bone (50%), in spheno-occipital region of the skull base (35%), and in the cervical, dorsal and lumbar spine (15%). Very rarely chordomas are found within sella, paranasal sinuses and nasopharynx, and in the forms of ectopic foci in the pons and spinal canal. Such tumour situated within spine destroys vertebral bodies and arches and can bulge into subdural space causing impression of the dural sac. Despite osteolytic destruction, chordomas cause visible reactive sclerotization and characteristic granular calcifications or ossifications. Intracranial chordomas destroy bony base of skull, specially clivus, pyramids and sphenoid sinuses.

摘要

脊索瘤通常发生于中轴骨骼,起源于脊索残余组织。其生长缓慢,常发生转移。此类病例主要见于40岁以上人群。脊索瘤最常位于骶骨(50%)、颅底蝶枕区(35%)以及颈椎、胸椎和腰椎(15%)。极少数情况下,脊索瘤可发生于蝶鞍、鼻窦和鼻咽部,以及脑桥和椎管内的异位病灶。位于脊柱的此类肿瘤会破坏椎体和椎弓,并可突入硬膜下间隙压迫硬膜囊。尽管有溶骨性破坏,但脊索瘤会引起明显的反应性硬化以及特征性的颗粒状钙化或骨化。颅内脊索瘤会破坏颅骨的骨性基底,尤其是斜坡、锥体和蝶窦。

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