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2至16岁土耳其儿童的脑瘫患病率。

Prevalence of cerebral palsy in Turkish children between the ages of 2 and 16 years.

作者信息

Serdaroğlu Ayse, Cansu Ali, Ozkan Seçil, Tezcan Sabahat

机构信息

Department of Paediatric Neurology, Gazi University Faculty of Medicine, Turkey.

出版信息

Dev Med Child Neurol. 2006 Jun;48(6):413-6. doi: 10.1017/S0012162206000910.

Abstract

The aim of this cross-sectional study was to determine the prevalence of cerebral palsy (CP) among children in Turkey between the ages of 2 and 16 years. Samples were selected from cities, towns, districts, and villages using the cluster sampling method; 41,861 children were selected. Data was collected by parental interview and physical examination. One hundred and eighty-six children were identified with CP. The prevalence of CP was determined as 4.4 per 1,000 live births and included postnatally acquired CP. Origin of CP was classified as prenatal in 49 (26.6%), perinatal/neonatal in 34 (18.5%), postnatal in 11 (5.9%), and unclassifiable in 90 participants (48.9%; data was unobtainable for two individuals). Type of CP was diplegia in 39.8% of children, hemiplegia in 28%, tetraplegia in 19.9%, ataxia in 5.9%, and dyskinetic in 6.4%. Prenatal factors were seen more frequently in the groups with a high socioeconomic status while perinatal factors were encountered more often in those with a low socioeconomic status (p<0.05). Place of residence and sex had no significant effect on the prevalence of CP (p>0.05). This cross-sectional study shows that the prevalence of CP in Turkey is higher than that in developed countries but the aetiology is probably similar. Although the high prevalence of CP in Turkey could originate from an increased level of obstetric and neonatal problems, the lack of a possible aetiological factor in approximately half the children suggests that the high level might also be due to other factors, such as genetic disorders.

摘要

这项横断面研究的目的是确定土耳其2至16岁儿童中脑瘫(CP)的患病率。采用整群抽样方法从城市、城镇、区和村庄选取样本;共选取了41,861名儿童。通过家长访谈和体格检查收集数据。共识别出186名患有脑瘫的儿童。脑瘫的患病率确定为每1000例活产中有4.4例,包括产后获得性脑瘫。脑瘫的起源分类为产前的有49例(26.6%),围产期/新生儿期的有34例(18.5%),产后的有11例(5.9%),90名参与者(48.9%;两名个体的数据无法获取)无法分类。脑瘫类型中,39.8%的儿童为双瘫,28%为偏瘫,19.9%为四肢瘫,5.9%为共济失调,6.4%为运动障碍型。产前因素在社会经济地位较高的群体中更为常见,而围产期因素在社会经济地位较低的群体中更为常见(p<0.05)。居住地和性别对脑瘫患病率无显著影响(p>0.05)。这项横断面研究表明,土耳其脑瘫的患病率高于发达国家,但病因可能相似。尽管土耳其脑瘫患病率高可能源于产科和新生儿问题的增加,但约一半儿童缺乏可能的病因因素表明高患病率也可能归因于其他因素,如遗传疾病。

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