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Lemierre's syndrome: case report in a pediatric patient.

作者信息

Litterio M R, Soto A E, Aguirre C B, Uranga M, Rubeglio E

机构信息

Servicio de Microbiología, Hospital Nacional de Pediatría Dr Prof.J.P.Garrahan, Combate de los Pozos 1881 (C1425AAM), Buenos Aires, Argentina.

出版信息

Anaerobe. 2004 Jun;10(3):151-4. doi: 10.1016/j.anaerobe.2004.03.001.

Abstract

Lemierre's syndrome was described in 1936 as a severe oropharyngeal infection followed by septic thrombophlebitis of the internal jugular vein and disseminated metastatic infections. Cases occur typically in previously healthy young adults and children. Fusobacterium necrophorum is the main anaerobic bacterium implicated. We present a septic 2-month-old infant with mastoiditis, multiple sites of osteoarthritis and multiple subcutaneous abscesses. No underlying anatomic or immunologic abnormalities were identified. Fusobacterium necrophorum was recovered from blood and bone samples obtained intraoperatively. Treatment included anaerobic coverage and drainage of septic foci. The patient was discharged home on 35th hospital day with oral amoxicillin-clavulanic acid and he recovered without sequelae. This was the first case of Lemierre's syndrome in our hospital. We want to highlight the absence of jugular vein thrombophlebitis, the presence of mastoiditis as previous infection and the surprising appearance of this infection in an edentulous 2-month-old infant.

摘要

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