胆结石疾病手术后肺部并发症的风险。

The risk of pulmonary complication after surgery for gallstone disease.

作者信息

Jiang Shan-Ping, Huang Li-Wen, Zhao Yi-Li, Min Jun, Wang Jie

机构信息

Department of Respiratory Medicine, The Second Affiliated Hospital, Sun Yat-Sen University, GuangZhou, China.

出版信息

Eur Rev Med Pharmacol Sci. 2006 Mar-Apr;10(2):41-6.

PMID:16705946

Abstract

OBJECTIVES

To identify the risk factors of postoperative pulmonary complications (PPC) after surgery for gallstone disease.

METHODS

A total of 544 patients undergoing open surgery for gallstone disease were retrospectively studied. Univariate and multivariate logistic regression were used to analyze each factor.

RESULTS

There were 24 factors relating to PPC in univariate logistic analysis. And multivariate logistic analysis identified 5 independent risk factors associated with PPC, including perioperative aerosol therapy (OR = 5.906), duration of postoperative antacids therapy (OR = 1.145), duration of operation (OR = 1.011), preoperative serum albumin (OR = 0.689), postoperative analgesia (OR = 0.059), Logistic regression equation for predicting the risk of PPC was P(1) = 1/[1 + e-(- 9.803 + 1.776 x A + 0.135 x B + 0.011 x C - 0.372 x D - 2.835 x E)].

CONCLUSION

Perioperative aerosol therapy, duration of postoperative antacids therapy, duration of operation, preoperative serum albumin and postoperative analgesia were independent risk factors associated with PPC in patients undergoing surgery for gallstone disease.

摘要

目的

确定胆结石疾病手术后肺部并发症（PPC）的危险因素。

方法

回顾性研究了544例接受胆结石疾病开放手术的患者。采用单因素和多因素逻辑回归分析各因素。

结果

单因素逻辑分析中有24个与PPC相关的因素。多因素逻辑分析确定了5个与PPC相关的独立危险因素，包括围手术期雾化治疗（OR = 5.906）、术后抗酸剂治疗时间（OR = 1.145）、手术时间（OR = 1.011）、术前血清白蛋白（OR = 0.689）、术后镇痛（OR = 0.059），预测PPC风险的逻辑回归方程为P(1) = 1/[1 + e-(- 9.803 + 1.776 x A + 0.135 x B + 0.011 x C - 0.372 x D - 2.835 x E)]。