Kaji Yoshiaki, Hirata Koichi, Ebata Atsuko
Department of Neurology, Dokkyo Medical University, Mibu, Japan.
Neuropsychobiology. 2006;53(3):148-52. doi: 10.1159/000093340. Epub 2006 May 16.
Post-stroke depression (PSD) has an important impact on the quality of life of patients with stroke. We studied 100 stroke patients (mean age+/-SD: 64.6+/-11.6, range: 32-85 years) in the subacute phase (2-5 weeks after onset) and investigated the prevalence and clinical correlates of PSD in the subacute phase. The prevalences of PSD and major depression in the subacute phase evaluated by the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, were 20.0 and 5.0%, respectively. These values were lower than those reported in Caucasian studies. The Zung Self-Rating Depression Scale (SDS) did not underestimate the presence of PSD and was thus considered valuable for the initial screening of PSD. However, SDS may overestimate PSD especially in patients with anxiety disorders or somatoform disorders and vice versa. Apathy was observed in 40.2% of patients; however, it was widely distributed and observed even in patients without serious depression.
中风后抑郁（PSD）对中风患者的生活质量有重要影响。我们研究了100例处于亚急性期（发病后2 - 5周）的中风患者（平均年龄±标准差：64.6±11.6，范围：32 - 85岁），并调查了亚急性期PSD的患病率及其临床相关因素。根据《精神疾病诊断与统计手册》第四版评估，亚急性期PSD和重度抑郁的患病率分别为20.0%和5.0%。这些数值低于高加索人群研究报告的结果。zung自评抑郁量表（SDS）并未低估PSD的存在，因此被认为对PSD的初步筛查有价值。然而，SDS可能高估PSD，尤其是在患有焦虑症或躯体形式障碍的患者中，反之亦然。40.2%的患者存在淡漠；然而，淡漠分布广泛，即使在没有严重抑郁的患者中也有发现。
