Szikora I, Berentei Z, Kulcsar Z, Barath K, Berez A, Bose A, Nyary I
National Institute of Neurosurgery, Budapest, Hungary.
Acta Neurochir (Wien). 2006 Jul;148(7):711-23; discussion 723. doi: 10.1007/s00701-006-0785-6. Epub 2006 May 17.
To assess the feasibility and results of parent vessel stent reconstruction with balloon expandable and self-expandable stents in the treatment of intracranial aneurysms.
In a total of 18 aneurysms balloon expandable (group A) and self expandable (group B) stents were used in 9 cases each. Stent implantation alone was used in 3 cases, and additional coil packing in the other 15.
Stents were successfully deployed in 8 out of 9 in group A and in 9 out of 9 cases in group B. Nearly complete occlusion was achieved in all but one case. At 3 or 6 months stable occlusion was found in 4 group A and 2 group B patients, progressive thrombosis in 3 cases in both groups, and recanalisation in 1 case in group B. Late follow up at 1-4 years demonstrated one progressive thrombosis one recanalisation and 1 stable occlusion in 3 group A, and 2 stable occlusions in 2 group B. patients. Complications included one aneurysm perforation in group A, one in-stent thrombosis and a distal arterial perforation in group B and one groin hematoma in both groups.
Stent reconstruction of intracranial arteries harbouring aneurysms is feasible and may result in aneurysm thrombosis without coil packing in some cases. Self expanding stents seem to provide a higher rate of success. Aggressive antiplatelet treatment increases the risk of hemorrhagic complications.
评估使用球囊扩张式和自膨式支架进行母血管支架重建术治疗颅内动脉瘤的可行性及效果。
总共18个动脉瘤,球囊扩张式支架(A组)和自膨式支架(B组)各用于9例。单独使用支架植入术3例,另外15例加用弹簧圈填塞。
A组9例中有8例成功植入支架,B组9例均成功植入。除1例之外所有病例均实现近完全闭塞。在3或6个月时,A组4例和B组2例发现闭塞稳定,两组各有3例出现进行性血栓形成,B组有1例再通。1至4年的后期随访显示,A组3例中有1例进行性血栓形成、1例再通和1例闭塞稳定,B组2例中有2例闭塞稳定。并发症包括A组1例动脉瘤穿孔,B组1例支架内血栓形成和1例远端动脉穿孔,两组各有1例腹股沟血肿。
对伴有动脉瘤的颅内动脉进行支架重建是可行的,在某些情况下可不使用弹簧圈填塞而使动脉瘤形成血栓。自膨式支架似乎成功率更高。积极的抗血小板治疗会增加出血性并发症的风险。