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使用扫描液体电离室电子射野影像装置进行二维透射剂量测量。

Two-dimensional transmitted dose measurements using a scanning liquid ionization chamber EPID.

作者信息

Mohammadi Mohammad, Bezak Eva

机构信息

Department of Medical Physics, Royal Adelaide Hospital, Adelaide, SA 5000, Australia.

出版信息

Phys Med Biol. 2006 Jun 7;51(11):2971-85. doi: 10.1088/0031-9155/51/11/019. Epub 2006 May 24.

Abstract

The use of a scanning liquid ionization chamber electronic portal imaging device (SLIC-EPID) for two-dimensional transmitted dosimetry was investigated and a calibration method was developed using extended dose range (EDR2) film. In order to convert pixel value to dose, the acquired SLIC-EPID pixel values were calibrated using an ionization chamber on the central axis. The relationship between pixel values, dose rate and absorbed dose was identified for various linac output repetition rates. To correct EPIs for dosimetric purposes, the off-axis ratio of dose profiles measured by EPIDs and EDR2 film was used to derive correction factor matrices (CFMs) for a range of source-to-EPID distances (SEDs). The corrected relative dose maps acquired for different conditions, including open and wedged fields, measured using a SLIC-EPID were compared with EDR2 film images using a gamma function algorithm with distance to agreement (DTA) = 2.5 mm and dose difference (DeltaDmax) = 1% criteria. The results showed that (a) for two-dimensional dosimetric purposes, EPIDs must be calibrated using appropriate two-dimensional correction factors and (b) SLIC-EPIDs can be used to measure the transmitted dose with good accuracy.

摘要

研究了使用扫描液体电离室电子射野成像装置(SLIC-EPID)进行二维透射剂量测定,并开发了一种使用扩展剂量范围(EDR2)胶片的校准方法。为了将像素值转换为剂量,使用中心轴上的电离室对采集到的SLIC-EPID像素值进行校准。确定了各种直线加速器输出重复率下像素值、剂量率和吸收剂量之间的关系。为了进行剂量测定目的的射野影像(EPI)校正,使用EPID和EDR2胶片测量的剂量分布离轴比来推导一系列源到EPID距离(SED)的校正因子矩阵(CFM)。使用距离一致性(DTA)=2.5 mm和剂量差异(DeltaDmax)=1%标准的伽马函数算法,将使用SLIC-EPID测量的不同条件(包括开放野和楔形野)下获取的校正相对剂量图与EDR2胶片图像进行比较。结果表明:(a)对于二维剂量测定目的,必须使用适当的二维校正因子对EPID进行校准;(b)SLIC-EPID可用于高精度测量透射剂量。

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