Chast François, Brandely Marie-Laure, Bardin Christophe
Service de Pharmacie, Pharmacologie, Toxicologie de l'Hôtel-Dieu, 1 place du Parvis Notre-Dame, 75181 Paris Cedex 04.
Bull Acad Natl Med. 2005 Nov;189(8):1721-32; discussion 1732-3.
Medication errors can lead to treatment failure and adverse drug reactions with potentially life-threatening consequences, especially when the patient is fragile or the drug is highly toxic. Both these latter factors are frequent in the cancer setting. Computers can be used to securitize the prescription (through validated protocols), preparation and administration of anticancer drugs, including experimental drugs, as they can store a wealth of information on both the individual patient and the product. We report our experience at Hotel-Dieu Hospital in Paris, where a computerized anticancer drug distribution system has increased treatment safety, provided major cost savings, and allowed nurses to spend more time with their patients.
用药错误可能导致治疗失败和药物不良反应，甚至可能带来危及生命的后果，尤其是当患者身体虚弱或药物毒性很强时。后两种因素在癌症治疗环境中很常见。计算机可用于确保抗癌药物（包括实验性药物）处方（通过经过验证的方案）、配制和给药的安全性，因为它们可以存储大量有关个体患者和药物产品的信息。我们报告了我们在巴黎迪厄医院的经验，在那里，一个计算机化的抗癌药物分发系统提高了治疗安全性，节省了大量成本，并使护士有更多时间陪伴患者。
