敲响胰岛素的晚餐铃：毒蕈碱型M3受体在胰腺β细胞功能调控中的作用
Ringing the dinner bell for insulin: muscarinic M3 receptor activity in the control of pancreatic beta cell function.
作者信息
Gromada Jesper, Hughes Thomas E
机构信息
Diabetes and Metabolism Disease Area, Novartis Institutes for BioMedical Research, 100 Technology Square, Cambridge, Massachusetts 02139, USA.
出版信息
Cell Metab. 2006 Jun;3(6):390-2. doi: 10.1016/j.cmet.2006.05.004.
PMID:16753574
Abstract
In this issue of Cell Metabolism, Gautam et al. (2006) show that pancreatic beta cell M3 muscarinic acetylcholine receptors control insulin secretion. Their results highlight the role of the M3 receptor subtype in integrating nervous stimuli with metabolic control of insulin secretion and glucose homeostasis.
摘要
在本期《细胞代谢》杂志中，高塔姆等人（2006年）表明，胰腺β细胞的M3型毒蕈碱型乙酰胆碱受体控制胰岛素分泌。他们的研究结果突出了M3受体亚型在整合神经刺激与胰岛素分泌及葡萄糖稳态的代谢控制方面的作用。
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