Bernhardt Peter, Steffens Michael, Kleinertz Klaus, Morell Roland, Budde Rainer, Leischik Roman, Krämer Alfred, Overhoff Ulrich, Strohm Oliver
Cardiac MRI-Center, Hospital Agatharied, Hausham, Germany.
J Cardiovasc Magn Reson. 2006;8(3):475-8. doi: 10.1080/10976640600575270.
Contrast-enhanced magnetic resonance imaging (ceMRI) allows for the detection of ischemic heart disease. Aim of this prospective study was to show feasibility, practicability and safety of adenosine stress ceMRI in routine outpatients with a mobile scanner.
Consecutive patients were scanned in six different cardiac outpatient centers with a 1.5 T mobile ceMRI scanner. First-pass wash-in patterns of gadolinium chelate were evaluated after three minutes of adenosine infusion. After a second bolus of gadolinium chelate myocardial late enhancement (MLE) images of the left ventricle were acquired to visualize myocardial necrosis.
Five hundred seventy-four patients were enrolled to the study. No major complications during examination and adenosine infusion were observed. One hundred seventy-three minor complications as temporary atrio-ventriculare blockade, mild chest pain or dyspnea and nausea were noticed. None of the complications led to further special treatment
This ceMRI protocol is suitable for application in outpatient settings. CeMRI stress testing using a mobile scanner in an outpatient setting is feasible and safe.
对比增强磁共振成像(ceMRI)可用于检测缺血性心脏病。这项前瞻性研究的目的是证明在常规门诊患者中使用移动扫描仪进行腺苷负荷ceMRI的可行性、实用性和安全性。
连续患者在六个不同的心脏门诊中心使用1.5T移动ceMRI扫描仪进行扫描。在输注腺苷三分钟后评估钆螯合物的首过灌注模式。在第二次注射钆螯合物后,采集左心室心肌延迟强化(MLE)图像以观察心肌坏死情况。
574例患者纳入本研究。检查和腺苷输注期间未观察到重大并发症。注意到173例轻微并发症,如暂时性房室传导阻滞、轻度胸痛或呼吸困难以及恶心。所有并发症均未导致进一步的特殊治疗。
该ceMRI方案适用于门诊环境。在门诊环境中使用移动扫描仪进行ceMRI负荷试验是可行且安全的。