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[使用弗明汉函数评估西班牙加那利群岛人群的冠心病风险]

[Coronary risk in the population of the Canary Islands, Spain, using the Framingham function].

作者信息

Cabrera de León Antonio, Rodríguez-Pérez María del Cristo, del Castillo-Rodríguez José Carlos, Brito-Díaz Buenaventura, Pérez-Méndez Lina I, Muros de Fuentes Mercedes, Almeida-González Delia, Batista-Medina Marta, Aguirre-Jaime Armando

机构信息

Unidad de Investigación, Hospital de la Candelaria, Santa Cruz de Tenerife, España.

出版信息

Med Clin (Barc). 2006 Apr 15;126(14):521-6. doi: 10.1157/13087138.

DOI:10.1157/13087138
PMID:16756902
Abstract

BACKGROUND AND OBJECTIVE

Although ischemic cardiopathy mortality in the Canary Islands is among the highest in Spain, the specific coronary risk for its population has not been estimated. This study presents the first cardiovascular risk charts for the Canarian adult population and compares them with those previously published on Gerona, Spain.

SUBJECTS AND METHOD

A cross-sectional study of 4915 subjects, aged 25-74, that had been enrolled in the cohort study CDC of the Canary Islands. The standardized prevalence of obesity, overweight, smoking, hypertension and diabetes were estimated with the information obtained from personnel interviews, physical exams and blood samples. Those prevalences were used to calibrate the Framingham coronary function and to elaborate coronary risk charts.

RESULTS

The crude prevalence of obesity was 30% (95% confidence interval [CI], 28.7-31.3), overweight 39% (95% CI, 37.6-40.4), smoking 26% (95% CI, 24.8-27.2), hypertension 40% (95% CI, 38.6-41.4) and diabetes 12% (95% CI, 11.1-12.9). In most of the factors, these prevalences were higher than Gerona's population in every age group and gender. On average, the estimated coronary risk of the islanders was 89% higher than Gerona's risk (94% higher in males and 87% in females), which is concordant with the distance between both populations in the national mortality statistics.

CONCLUSIONS

The high prevalence of obesity and other factors in the Canarian population implies important coronary risks and it explains the position of the Canary Islands in the Spanish statistics of ischemic cardiopathy mortality. The use of these calibrated risk charts would be helpful to intensify the prevention of cardiovascular diseases.

摘要

背景与目的

尽管加那利群岛的缺血性心脏病死亡率在西班牙位居前列,但其居民的具体冠状动脉风险尚未得到评估。本研究给出了加那利群岛成年人群的首张心血管风险图表,并将其与此前在西班牙赫罗纳发布的图表进行比较。

对象与方法

对4915名年龄在25 - 74岁之间、参与加那利群岛疾病控制中心队列研究的对象进行横断面研究。通过人员访谈、体格检查和血液样本获取的信息,估算肥胖、超重、吸烟、高血压和糖尿病的标准化患病率。这些患病率用于校准弗雷明汉冠状动脉功能并绘制冠状动脉风险图表。

结果

肥胖的粗患病率为30%(95%置信区间[CI],28.7 - 31.3),超重为39%(95% CI,37.6 - 40.4),吸烟为26%(95% CI,24.8 - 27.2),高血压为40%(95% CI,38.6 - 41.4),糖尿病为12%(95% CI,11.1 - 12.9)。在大多数因素方面,这些患病率在各年龄组和性别中均高于赫罗纳的人群。平均而言,岛民的估计冠状动脉风险比赫罗纳的风险高89%(男性高94%,女性高87%),这与两国死亡率统计中这两个人群之间的差距一致。

结论

加那利群岛人群中肥胖及其他因素的高患病率意味着重要的冠状动脉风险,这也解释了加那利群岛在西班牙缺血性心脏病死亡率统计中的位置。使用这些校准后的风险图表将有助于加强心血管疾病的预防。

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