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噪声暴露回顾性测量的预测效度。

Predictive validity of a retrospective measure of noise exposure.

作者信息

McNamee R, Burgess G, Dippnall W M, Cherry N

机构信息

Division of Epidemiology and Health Sciences, University of Manchester, Manchester, UK.

出版信息

Occup Environ Med. 2006 Dec;63(12):808-12. doi: 10.1136/oem.2006.026534. Epub 2006 Jun 6.

Abstract

AIMS

To investigate the validity of measures of noise exposure derived retrospectively for a cohort of nuclear energy workers for the period 1950-98, by investigating their ability to predict hearing loss.

METHODS

Subjects were men aged 45-65 chosen from a larger group of employees--assembled for a nested case-control study of noise and death from ischaemic heart disease--who had had at least one audiogram after at least five years' work. Average hearing loss, across both ears and the frequencies 0.5, 1, 2, and 4 kHz, was calculated from the last audiogram for each man. Previous noise exposure at work was assessed retrospectively by three hygienists using work histories, noise survey records from 1965-98, and judgement about use of hearing protection devices. Smoking and age at the time of the audiogram were extracted from records. Differences in hearing loss between men categorised by cumulative noise exposure were assessed after controlling for age, smoking, year of test, and previous test experience.

RESULTS

There were 186 and 150 eligible subjects at sites A and B of the company respectively who were employed for an average of 20 years. Compared to men with less than one year's exposure to levels of 85dB(A) or greater, hearing loss was greater by 3.7 dB (90% CI -2.6 to 10.1), 3.8 dB (90% CI -2.6 to 10.3), 7.0 dB (90% CI 1.1 to 12.9) and 10.1 dB (90% CI 4.2 to 16.0) in the lowest to highest categories of cumulative noise exposure at site B. In contrast, at site A, the corresponding figures were -2.2 dB, -2.4 dB, -1.8 dB, and -4.4 dB, with no confidence interval excluding zero.

CONCLUSIONS

Noise estimation at one site was shown to have predictive validity in terms of hearing loss, but not at the other site. Reasons for the differences between sites are discussed.

摘要

目的

通过研究回顾性得出的1950 - 1998年期间一群核能工作者的噪声暴露测量值预测听力损失的能力,来调查其有效性。

方法

研究对象为年龄在45 - 65岁之间的男性,他们选自一个更大的员工群体(该群体为一项关于噪声与缺血性心脏病死亡的巢式病例对照研究而组建),且在工作至少五年后至少进行过一次听力图检查。根据每个人最后一次听力图计算双耳在0.5、1、2和4千赫频率处的平均听力损失。三名卫生学家通过工作经历、1965 - 1998年的噪声调查记录以及对听力保护设备使用情况的判断,回顾性评估之前的工作噪声暴露情况。从记录中提取听力图检查时的吸烟情况和年龄。在控制年龄、吸烟、检查年份和之前的检查经历后,评估按累积噪声暴露分类的男性之间的听力损失差异。

结果

该公司A、B两个地点分别有186名和150名符合条件的受试者,他们平均工作了20年。在B地点,与暴露于85分贝(A)或更高水平少于一年的男性相比,累积噪声暴露从最低到最高类别,听力损失分别增加了3.7分贝(90%置信区间 - 2.6至10.1)、3.8分贝(90%置信区间 - 2.6至10.3)、7.0分贝(90%置信区间1.1至12.9)和10.1分贝(90%置信区间4.2至16.0)。相比之下,在A地点,相应数字分别为 - 2.2分贝、 - 2.4分贝、 - 1.8分贝和 - 4.4分贝,且没有置信区间排除零。

结论

在一个地点的噪声估计在听力损失方面显示出预测有效性,但在另一个地点则不然。讨论了不同地点之间差异的原因。

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本文引用的文献

1
Occupational noise exposure and ischaemic heart disease mortality.
Occup Environ Med. 2006 Dec;63(12):813-9. doi: 10.1136/oem.2005.026245. Epub 2006 Aug 15.
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Assessing historical exposure is like solving a mystery.
Occup Environ Med. 2005 Jul;62(7):429-30. doi: 10.1136/oem.2004.019158.
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