Sobel-Maruniak Anna, Grzywa Marek, Orłowska-Florek Renata, Staniszewski Andrzej
Department of Internal Medicine, Nephrology and Endocrinology with the Nuclear Medicine Unit, Regional Hospital No. 2, Rzeszów.
Endokrynol Pol. 2006 Mar-Apr;57(2):127-30.
Studies carried out over the last few years have provided information about the increase in the incidence of type 1 diabetes in different parts of the world including the European countries bordering Poland.
The aim of this study was to determine the long-term trends in the incidence of type 1 diabetes over the 20 years between 1980 and 1999 and to compare the incidence during the decades preceding and following the 1989 economic and political transformation in Poland.
The registration of type 1 diabetes among people aged 0-29 was drawn up according to the DERI recommendations using three data sources. We calculated the age-standardised incidence rates for five-year age groups and determined the long-term trend in the incidence of type 1 diabetes in south-eastern Poland.
A significant growth in the incidence of type 1 diabetes was observed among people aged 0-29 in the Rzeszów Province in the period between 1980 and 1999. The mean age-standardised incidence rate was 6.1/100,000, and a statistically significant difference was noted between the 1980s and the 1990s (5.3 [95%CI 4.5-6.0] and 6.8 [95%CI 5.9-7.6]). The male incidence of 6.7 significantly exceeded that for females--5.5/100,000. There was also a higher incidence in the group aged 0-14 in comparison with the group aged 15-29 (6.4 and 5.8/100,000 respectively). The highest incidence was found in boys aged 10-14 (11.5/100,000) and a significantly rising trend was observed in children of 0-4 years old.
The mean incidence of type 1 diabetes among the study population was low. Nevertheless, we demonstrated a significantly increasing trend in the incidence during the 20-year observation period. The incidence in the 1990s, both in general and for males, was significantly higher when compared to the 1980s.
过去几年开展的研究提供了有关世界不同地区1型糖尿病发病率上升的信息,包括与波兰接壤的欧洲国家。
本研究的目的是确定1980年至1999年这20年间1型糖尿病发病率的长期趋势,并比较波兰1989年经济和政治变革前后几十年的发病率。
根据DERI建议,使用三个数据源编制了0至29岁人群中1型糖尿病的登记资料。我们计算了五岁年龄组的年龄标准化发病率,并确定了波兰东南部1型糖尿病发病率的长期趋势。
1980年至1999年期间,热舒夫省0至29岁人群中1型糖尿病发病率显著上升。平均年龄标准化发病率为6.1/10万,20世纪80年代和90年代之间存在统计学显著差异(5.3[95%CI 4.5 - 6.0]和6.8[95%CI 5.9 - 7.6])。男性发病率为6.7,显著超过女性发病率——5.5/10万。0至14岁年龄组的发病率也高于15至29岁年龄组(分别为6.4和5.8/10万)。发病率最高的是10至14岁的男孩(11.5/10万),并且在0至4岁儿童中观察到显著上升趋势。
研究人群中1型糖尿病的平均发病率较低。然而,我们在20年观察期内证明了发病率有显著上升趋势。与20世纪80年代相比,90年代的发病率总体上以及男性发病率均显著更高。