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慢性阻塞性肺疾病(COPD)从首次入院到死亡所导致的住院负担。

The COPD-induced hospitalization burden from first admission to death.

作者信息

Kinnunen Tuija, Säynäjäkangas Olli, Keistinen Timo

机构信息

Ostrobothnia Hospital District, Mariankatu 16-20, FIN 67200 Kokkola, Finland.

出版信息

Respir Med. 2007 Feb;101(2):294-9. doi: 10.1016/j.rmed.2006.05.004. Epub 2006 Jun 13.

Abstract

BACKGROUND

Hospitalization periods at the exacerbation stage of COPD place a major burden on the health services and entail substantial costs. Little is known, however, about the corresponding burden on hospitals as the disease advances. We therefore set out to determine from hospital discharge and cause of death registers the overall burden on hospital resources occasioned by a COPD patient on a relative time scale from first admission to death, differentiated by age group, prognosis and sex.

METHODS

Data on all subsequent hospital treatment periods after the first for patients with COPD who were over 44 years of age on admission were gathered from the Finnish National Research and Development Centre for Welfare and Health for the period 1991-2001. The actual material for this study consisted of the data on those patients who were alive after the first treatment period but had died by 2001. These were divided into three survival groups.

RESULTS

The 8325 patients in this material had a total of 35,814 hospitalization periods in 1991-2001, of which men accounted for 73.6%. A total of 1895 of the patients (22.8%) had died within a year, 4257 (51.1%) within 1-5 years and 2173 (26.1%) after more than 5 years. Of those dying within a year, 20.9% had been in hospital care, while of those who lived on for over a year, 4.5% were in hospital when two-thirds of their remaining lifetime was still ahead of them and 7.3% when one-tenth of that time was still ahead.

CONCLUSIONS

Almost one-fourth of the COPD patients had died within a year of first hospital admission for the disease. This group with a poor prognosis made abundant use of hospital services. The burden imposed on such services by severe COPD patients is U-shaped, with hospital use increasing towards the end of their lives.

摘要

背景

慢性阻塞性肺疾病(COPD)加重期的住院时间给卫生服务带来了重大负担,并产生了巨额费用。然而,对于随着疾病进展给医院带来的相应负担,人们知之甚少。因此,我们着手从医院出院和死亡原因登记册中确定COPD患者从首次入院到死亡的相对时间尺度上对医院资源造成的总体负担,并按年龄组、预后和性别进行区分。

方法

从芬兰国家福利与健康研究发展中心收集了1991年至2001年期间44岁以上首次入院的COPD患者所有后续住院治疗期的数据。本研究的实际资料包括首次治疗期后存活但到2001年已死亡的患者的数据。这些患者被分为三个生存组。

结果

该资料中的8325名患者在1991年至2001年期间共有35814个住院期,其中男性占73.6%。共有1895名患者(22.8%)在一年内死亡,4257名(51.1%)在1至5年内死亡,2173名(26.1%)在5年以上死亡。在一年内死亡的患者中,20.9%曾接受住院治疗,而存活超过一年的患者中,在其剩余寿命的三分之二时仍有4.5%住院,在剩余寿命的十分之一时仍有7.3%住院。

结论

近四分之一的COPD患者在首次因该疾病住院后的一年内死亡。这一预后不良的群体大量使用了医院服务。重度COPD患者给此类服务带来的负担呈U形,在其生命末期医院使用率增加。

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