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无创正压通气可预防慢性呼吸机使用者术后肺部并发症。

Noninvasive positive pressure ventilation prevents postoperative pulmonary complications in chronic ventilators users.

作者信息

Lumbierres M, Prats E, Farrero E, Monasterio C, Gracia T, Manresa F, Escarrabill J

机构信息

UFIS-Respiratoria, Servei de Pneumología, Hospital Universitari de Bellvitge, Feixa Llarga s/n, 08907 L'Hospitalet Llobregat, Barcelona, Spain.

出版信息

Respir Med. 2007 Jan;101(1):62-8. doi: 10.1016/j.rmed.2006.04.012. Epub 2006 Jun 13.

Abstract

OBJECTIVE

To evaluate the postoperative pulmonary complications and the long-term impact on pulmonary function of different surgical procedures with general anaesthesia in chronic respiratory failure (CRF) patients who were using noninvasive positive pressure ventilation (NPPV).

DESIGN

We retrospectively studied 20 stable patients on NPPV for CRF secondary to: kyphoscoliosis (eight), morbid obesity (six), thoracoplasty (four), neuromuscular diseases (two), who underwent surgical procedures with general anaesthesia, between January 1998 and December 2003.

MATERIAL AND METHODS

The variables studied were: type of surgery, hours of orotracheal intubation, hours of stay in the postsurgical reanimation unit (PRU), postoperative pulmonary complications and days of hospital stay. These results were compared with those obtained in patients without respiratory pathology and who were submitted to the same type of surgical interventions during the study period. All patients were tested for: arterial blood gases, forced vital capacity (FVC) and forced expiratory volume in 1s (FVE1). These tests were carried out both prior to surgical intervention and 12 months after this intervention, and the use of medical assistance resources the year prior to and the year after the surgical intervention were also analysed.

RESULTS

Sixteen patients were using NPPV at home at the time of the intervention and four patients were adapted to NPPV before surgery. The surgical procedures were: gastroplasty: six; mastectomy: five; septoplasty: three; hip prosthesis: two; cholecystectomy: one; Gasserian ganglion thermocoagulation: one; hysterectomy: one; and endoscopic retrograde cholangiopancreatography (ERCP): one. The mean postoperative intubation time was 3.8+/-3.2h, and only one patient remained intubated for more than 12h. The mean stay in the PRU was 19+/-9h (vs 19+/-6h in the general population, p>0.05). The days of hospital stay for the different pathologies were in the majority of cases greater than in the general population. We did not find significant differences on comparing the arterial blood gases, in pulmonary function or in use of assistance resources between the year previous to and the year following the surgical intervention.

CONCLUSIONS

In high-risk patients with chronic respiratory failure as a consequence of a restrictive lung pathology, NPPV can play an important role to confront surgical procedure with general anaesthesia with greater security. To obtain these results, it was fundamental to coordinate between the Pulmonary Services and the Anaesthesia Services as well as to follow up jointly in the PRU.

摘要

目的

评估在使用无创正压通气(NPPV)的慢性呼吸衰竭(CRF)患者中,不同全身麻醉手术方式的术后肺部并发症及对肺功能的长期影响。

设计

我们回顾性研究了20例因以下原因继发CRF且使用NPPV的稳定患者:脊柱后凸侧弯(8例)、病态肥胖(6例)、胸廓成形术(4例)、神经肌肉疾病(2例),这些患者在1998年1月至2003年12月期间接受了全身麻醉手术。

材料与方法

研究的变量包括:手术类型、口气管插管时间、术后复苏单元(PRU)停留时间、术后肺部并发症及住院天数。将这些结果与在研究期间接受相同类型手术干预且无呼吸疾病的患者所获结果进行比较。所有患者均进行了以下检测:动脉血气、用力肺活量(FVC)和第1秒用力呼气量(FVE1)。这些检测在手术干预前及干预后12个月进行,同时还分析了手术干预前一年和后一年医疗辅助资源的使用情况。

结果

16例患者在干预时在家中使用NPPV,4例患者在手术前已适应NPPV。手术方式包括:胃成形术:6例;乳房切除术:5例;鼻中隔成形术:3例;髋关节置换术:2例;胆囊切除术:1例;半月神经节热凝术:1例;子宫切除术:1例;内镜逆行胰胆管造影术(ERCP):1例。术后平均插管时间为3.8±3.2小时,仅1例患者插管时间超过12小时。在PRU的平均停留时间为19±9小时(普通人群为19±6小时,p>0.05)。不同病情的住院天数在大多数情况下多于普通人群。在比较手术干预前一年和后一年的动脉血气、肺功能或辅助资源使用情况时,我们未发现显著差异。

结论

在因限制性肺病导致慢性呼吸衰竭的高危患者中,NPPV可在更安全地应对全身麻醉手术方面发挥重要作用。为取得这些结果,肺科与麻醉科之间的协调以及在PRU的联合随访至关重要。

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