肾小球样血管瘤导致POEMS综合征的诊断。

Glomeruloid hemangioma leading to a diagnosis of POEMS syndrome.

作者信息

Phillips Julie A, Dixon Julie E, Richardson Jeffrey B, Fabre Vilma C, Callen Jeffrey P

机构信息

Division of Dermatology, University of Louisville, KY 40202, USA.

出版信息

J Am Acad Dermatol. 2006 Jul;55(1):149-52. doi: 10.1016/j.jaad.2006.02.036.

DOI:10.1016/j.jaad.2006.02.036

PMID:16781311

Abstract

POEMS is an acronym for polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes. It is a poorly understood paraneoplastic syndrome that stems from an underlying plasma cell dyscrasia. Of the skin changes, the glomeruloid hemangioma is considered to be a specific marker of POEMS syndrome. We describe a 68-year-old man who presented to his dermatologist with multiple hemangiomas, whose biopsy diagnosis of glomeruloid hemangioma resulted in further evaluation and an eventual diagnosis of POEMS.

摘要

POEMS是多发性神经病、器官肿大、内分泌病、单克隆蛋白和皮肤改变的首字母缩写。它是一种鲜为人知的副肿瘤综合征，源于潜在的浆细胞发育异常。在皮肤改变中，肾小球样血管瘤被认为是POEMS综合征的特异性标志物。我们描述了一名68岁男性，他因多发性血管瘤就诊于皮肤科医生，其肾小球样血管瘤的活检诊断促使进一步评估，最终确诊为POEMS。