Kovács Endre, Becker Dávid, Daróczi László, Gálfy Ildikó, Hüttl Tivadar, Laczkó Agnes, Paukovits Tamas, Vargha Péter, Szabolcs Zoltán
Semmelweis Egyetem Budapest, Er- és Szívsebeszeti Klinika, Budapest
Magy Seb. 2006 Apr;59(2):105-11.
Intraaortic balloon pump (IABP) is being used in cardiac surgery in an increased ratio. IABP therapy involves considerable risk, mainly vascular complications, postoperative bleeding and infection can represent danger. Between 1999 and 2004 out of 4443 open heart surgery operations we have performed intraaortic balloon pump treatment in case of 75 patients. The mean age was 64 years, 23 patients had diabetes mellitus, 47 patients had hypertension, 20 patients had peripheral vascular disease as well. We performed IABP therapy most frequently during isolated coronary bypass operations (42 cases), but also combined operations (implantation of valve prosthesis + coronary bypass) represent a significant part (implantation of aortic valve prosthesis + CABG: 5 cases, implantation of mitral valve prosthesis + CABG: 8 cases). Vascular complications occurred in 10 cases--13.3%--out of 75 patients, including 7 fatal ones. Three cases are due to the IABP treatment itself: Crush syndrome was developed leading to the loss of the patient. Applying the multiple logistic regression model we have examined the effect of the following factors on the occurrence of vascular complications: gender, age, body surface, accompanying diseases (hypertension, diabetes, peripheral vascular disease), the method and timing of insertion. Peripheral vascular disease (p < 0.005) and hypertension (p = 0.01) represent independent risk factors regarding the occurrence of complications. Having performed chi-square test we have not identified significant correlations between mortality and vascular complications. In case of prevailing peripheral vascular disease, the application of alternative insertion techniques--via the ascending aorta, the axillary artery--are recommended.
主动脉内球囊反搏(IABP)在心脏手术中的应用比例正在增加。IABP治疗存在相当大的风险,主要是血管并发症,术后出血和感染也可能构成危险。1999年至2004年期间,在我们进行的4443例心脏直视手术中,有75例患者接受了主动脉内球囊反搏治疗。患者平均年龄为64岁,其中23例患有糖尿病,47例患有高血压,20例还患有外周血管疾病。我们最常在单纯冠状动脉搭桥手术期间进行IABP治疗(42例),但联合手术(瓣膜置换术+冠状动脉搭桥术)也占相当大的比例(主动脉瓣置换术+CABG:5例,二尖瓣置换术+CABG:8例)。75例患者中有10例发生血管并发症,占13.3%,其中7例死亡。3例是由于IABP治疗本身导致的:发生挤压综合征导致患者死亡。我们应用多元逻辑回归模型研究了以下因素对血管并发症发生的影响:性别、年龄、体表面积、伴发疾病(高血压、糖尿病、外周血管疾病)、插入方法和时间。外周血管疾病(p<0.005)和高血压(p=0.01)是并发症发生的独立危险因素。我们进行卡方检验后未发现死亡率与血管并发症之间存在显著相关性。在存在外周血管疾病的情况下,建议采用替代插入技术——经升主动脉、腋动脉插入。