阿根廷科尔多瓦市重症监护病房患者中耐万古霉素肠球菌（VRE）的定植情况。
Colonization with vancomycin-resistant enterococci (VRE) in intensive care unit patients in Cordoba City, Argentina.
作者信息
Littvik A M, López T N, González S E, Fernández C M, Pavan J V
机构信息
Laboratorio de Microbiología, Hospital Rawson, Córdoba, Argentina.
出版信息
Rev Argent Microbiol. 2006 Jan-Mar;38(1):28-30.
The purpose of this study was to determine the prevalence of colonization with vancomycin-resistant enterococci (VRE) among intensive care unit (ICU) patients in a hospital in Córdoba, Argentina. We collected 235 rectal swab specimens from 147 ICU patients. Resistance to vancomycin was screened with the disk diffusion method, and MICs were determined with the E-test method. Vancomycin-resistant genotypes were determined by PCR. The VRE strains were isolated from 18/147 patients (12.2%). The isolates were identified as Enterococcus faecium (94.4%), and Enterococcus gallinarum (5.6%). PCR showed that the E. faecium strains carried the vanA gene, and the E. gallinarum strain carried the vanC1 gene. Our study indicated that at least 12.2% of ICU patients were VRE carriers.
本研究的目的是确定阿根廷科尔多瓦一家医院重症监护病房（ICU）患者中耐万古霉素肠球菌（VRE）的定植率。我们从147例ICU患者中收集了235份直肠拭子标本。采用纸片扩散法筛选对万古霉素的耐药性，并用E-test法测定最低抑菌浓度（MIC）。通过聚合酶链反应（PCR）确定耐万古霉素基因型。从18/147例患者（12.2%）中分离出VRE菌株。分离株鉴定为粪肠球菌（94.4%）和鹑鸡肠球菌（5.6%）。PCR显示粪肠球菌菌株携带vanA基因，鹑鸡肠球菌菌株携带vanC1基因。我们的研究表明，至少12.2%的ICU患者是VRE携带者。
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