Olson Leslie, Cravero Lynn, Kisthard Jim, Ward Scott, Marks William
LifeCenter Northwest, Bellevue, Wash, USA.
Prog Transplant. 2006 Jun;16(2):141-3. doi: 10.1177/152692480601600209.
Our organ procurement organization recently developed an aggressive donation after cardiac death program. Thoracic organs are rarely recovered from non-heart-beating donors. Therefore, there is concern that donation after cardiac death may affect the recovery of thoracic organs from donors not allowed to progress to brain death.
To evaluate the potential impact of donation after cardiac death on the recovery of thoracic organs.
On the assumption that prolongation of care on all cases would result in a diagnosis of brain death. By retrospective chart review, all donations after cardiac death were evaluated for thoracic organ potential using the same standards that were used to evaluate brain-dead donors.
During the study period there were 34 of 44 (77%) non-heart-beating donors qualified to donate abdominal organs only. Ten of 44 non-heart-beating donors (24%) qualified to potentially donate thoracic organs; the families of 4 of 10 of these donors insisted on the immediate withdrawal of life support, leaving only 6 donors with thoracic organ potential. All 6 of these donors qualified as potential heart donors and 3 as potential lung donors.
A total of 97 organs were recovered and successfully transplanted from 44 non-heart-beating donors. If all the donors who qualified to donate thoracic organs progressed to brain death and if their thoracic organs were transplantable, then 6 additional hearts and 3 pairs of lungs may have been recovered. These data demonstrate that an aggressive donation after cardiac death program contributes significantly to the organ donor pool, with a minimal impact on potential thoracic organ recovery.
我们的器官获取组织最近制定了一项积极的心脏死亡后捐赠计划。从非心跳供体获取胸段器官的情况很少见。因此,有人担心心脏死亡后捐赠可能会影响从不允许发展为脑死亡的供体获取胸段器官。
评估心脏死亡后捐赠对胸段器官获取的潜在影响。
假设对所有病例延长治疗都会导致脑死亡诊断。通过回顾性病历审查,使用与评估脑死亡供体相同的标准,对所有心脏死亡后捐赠进行胸段器官获取潜力评估。
在研究期间,44例非心跳供体中有34例(77%)仅符合捐赠腹部器官的条件。44例非心跳供体中有10例(24%)符合潜在捐赠胸段器官的条件;其中10例供体中有4例的家属坚持立即撤除生命支持,仅剩下6例有胸段器官获取潜力的供体。这6例供体均符合潜在心脏供体条件,3例符合潜在肺脏供体条件。
从44例非心跳供体中总共获取并成功移植了97个器官。如果所有符合捐赠胸段器官条件的供体都发展为脑死亡,并且其胸段器官可用于移植,那么可能会多获取6颗心脏和3对肺脏。这些数据表明,积极的心脏死亡后捐赠计划对器官供体库有显著贡献,对潜在胸段器官获取的影响最小。