Mohindra Sandeep, Gupta Sunil Kumar, Mohindra Satyawati, Gupta Rahul
Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
Surg Neurol. 2006 Jul;66(1):94-9; discussion 99. doi: 10.1016/j.surneu.2005.11.020.
CVJ tuberculosis is a described entity requiring challenging ways of management. Severe neck pain, causing restricted neck movements and torticollis, is a characteristic presentation of neurologically asymptomatic suboccipital Pott's disease.
Two patients with unusual CVJ tuberculosis form the basis for the present communication. The first patient presented with tubercular otitis media, causing progressive erosion of the petrous part of temporal bone, and destruction of the occipital condyle, along with the lateral mass of atlas, leading to CVJ instability. This is a first report of such a presentation, according to our knowledge. Detailed bony architectural destruction demonstrable on CT scan has been described. The second patient, with CVJ tuberculosis, presented with skull base syndrome and with multiple cranial nerve palsies. Both patients were managed without surgical intervention and showed clinical and radiological recovery.
In such patients with unusual clinical presentations, histopathologic examination is necessary to arrive at a correct diagnosis. The management of patients with tubercular involvement of CVJ remains controversial. In the present communication, both the patients were managed successfully with full dose of antitubercular drugs and immobilization.
寰枢椎结核是一种已被描述的疾病实体,其治疗方式具有挑战性。严重的颈部疼痛导致颈部活动受限和斜颈,是神经无症状性枕下结核性脊椎炎的典型表现。
两名患有不寻常寰枢椎结核的患者构成了本报告的基础。首例患者表现为结核性中耳炎,导致颞骨岩部进行性侵蚀,枕髁以及第一颈椎侧块破坏,进而导致寰枢椎不稳。据我们所知,这是此类表现的首例报告。文中描述了CT扫描显示的详细骨质结构破坏情况。第二例患有寰枢椎结核的患者表现为颅底综合征和多发性颅神经麻痹。两名患者均未接受手术干预,临床和影像学检查均显示康复。
对于此类临床表现不寻常的患者,进行组织病理学检查对于做出正确诊断是必要的。寰枢椎结核患者的治疗仍存在争议。在本报告中,两名患者均通过足量抗结核药物治疗和固定获得了成功治疗。