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脑膜瘤

Meningioma.

作者信息

Goldsmith Brian, McDermott Michael W

机构信息

Department of Neurological Surgery, University of California, San Francisco, 400 Parnassus, 8th Floor, San Francisco, CA 94143, USA.

出版信息

Neurosurg Clin N Am. 2006 Apr;17(2):111-20, vi. doi: 10.1016/j.nec.2006.03.002.

Abstract

Total excision is an appropriate treatment option for patients with benign meningiomas that are resectable with minimal morbidity. It is particularly appropriate for patients with significant mass effect causing symptoms. Fractionated conformal radiotherapy is an appropriate primary treatment option for patients with benign meningiomas of all sizes and all sites. It is particularly appropriate and preferred for optic nerve sheath meningiomas, for which there are few alternatives. Planned subtotal resection is appropriate if decompression is expected to relieve acute symptoms. After subtotal resection, it is appropriate to offer single-fraction radiosurgery or multifraction radiotherapy, depending on the size, location, and extent of residual tumor, so as to achieve progression-free survival and cause-specific survival rates comparable to those of other approaches.

摘要

对于可切除且并发症发生率极低的良性脑膜瘤患者,全切除是一种合适的治疗选择。对于有明显占位效应并引起症状的患者,这一方法尤为适用。分次适形放疗是各种大小和部位的良性脑膜瘤患者的一种合适的初始治疗选择。对于视神经鞘膜瘤,这一方法尤为适用且是首选,因为针对该病症几乎没有其他替代方案。如果预计减压可缓解急性症状,计划行次全切除是合适的。次全切除后,根据残留肿瘤的大小、位置和范围,给予单次分割放射外科治疗或多次分割放疗是合适的,以便实现无进展生存期和特定病因生存率,使其与其他治疗方法相当。

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