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手辅助腹腔镜输尿管松解术治疗特发性腹膜后纤维化继发的输尿管梗阻:一种新技术及初步病例系列评估

Hand-assisted laparoscopic ureterolysis to treat ureteral obstruction secondary to idiopathic retroperitoneal fibrosis: assessment of a novel technique and initial series.

作者信息

Brown James A, Garlitz Cristopher J, Hubosky Scott G, Gomella Leonard G

机构信息

Division of Urology, Medical College of Georgia, Augusta, Georgia 30912-4050, USA.

出版信息

Urology. 2006 Jul;68(1):46-9. doi: 10.1016/j.urology.2006.01.048. Epub 2006 Jun 27.

Abstract

OBJECTIVES

To describe a novel technique and assess an initial series of hand-assisted laparoscopic ureterolysis for the treatment of retroperitoneal fibrosis.

METHODS

Five patients (3 women and 2 men, mean age 56.4 years) with ureteral obstruction secondary to retroperitoneal fibrosis underwent bilateral hand-assisted laparoscopic ureterolysis with biopsy. These patients had undergone an imaging evaluation with excretory urography, computed tomography, furosemide washout nucleotide scan, and/or magnetic resonance imaging. All had ureteral stents placed before or at surgery. A periumbilical hand port, bilateral 10-mm perirectal camera ports, and bilateral 5-mm or 10-mm working ports were placed. The ureters were completely mobilized and placed intraperitoneally. The patient demographic, operative, and early and late postoperative data were collected.

RESULTS

The average operating room time was 259 minutes (range 215 to 300), and the estimated blood loss was 80 mL (range 50 to 200). The mean hospital stay was 4.20 days (range 3 to 5). One minor intraoperative ureteral injury and no postoperative complications occurred. The mean analgesic requirement was 45.6 mg morphine sulfate (range 20 to 88). Three patients also received 120 mg of parenteral ketorolac. All indwelling ureteral stents were removed by 2 to 4 weeks postoperatively. At 22.4 months (range 12 to 29) postoperatively, 90% of the renal units were unobstructed.

CONCLUSIONS

Hand-assisted laparoscopic ureterolysis is an effective minimally invasive technique with less morbidity than open ureterolysis. It offers a shorter operative time and is less technically challenging than conventional laparoscopy. It is our preferred surgical approach for obstructive retroperitoneal fibrosis.

摘要

目的

描述一种新技术,并评估一系列初步的手辅助腹腔镜输尿管松解术治疗腹膜后纤维化的效果。

方法

5例(3例女性和2例男性,平均年龄56.4岁)因腹膜后纤维化导致输尿管梗阻的患者接受了双侧手辅助腹腔镜输尿管松解术及活检。这些患者均接受了排泄性尿路造影、计算机断层扫描、速尿洗脱核苷酸扫描和/或磁共振成像等影像学评估。所有患者在手术前或手术时均放置了输尿管支架。于脐周置入一个手辅助端口、双侧10毫米直肠旁摄像端口以及双侧5毫米或10毫米操作端口。将输尿管完全游离并置于腹腔内。收集患者的人口统计学、手术及术后早期和晚期数据。

结果

平均手术时间为259分钟(范围215至300分钟),估计失血量为80毫升(范围50至200毫升)。平均住院时间为4.20天(范围3至5天)。术中发生1例轻微输尿管损伤,无术后并发症。平均镇痛需求量为45.6毫克硫酸吗啡(范围20至88毫克)。3例患者还接受了120毫克胃肠外酮咯酸。所有留置的输尿管支架在术后2至4周取出。术后22.4个月(范围12至29个月)时,90%的肾单位无梗阻。

结论

手辅助腹腔镜输尿管松解术是一种有效的微创技术,与开放输尿管松解术相比,发病率更低。它手术时间较短,技术难度低于传统腹腔镜手术。它是我们治疗梗阻性腹膜后纤维化的首选手术方法。

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