Plantin Ingrid, Arnbjörnsson Einar, Larsson Lars-Torsten
Department of Paediatric Surgery, University Hospital, 221 85, Lund, Sweden.
Pediatr Surg Int. 2006 Jul;22(7):581-4. doi: 10.1007/s00383-006-1707-7. Epub 2006 Jun 1.
The objective of the study was to assess the influence of a laparoscopic video-assisted gastrostomy on acid gastroesophageal reflux (GER). A prospective uncontrolled study included 23 neurologically disabled children, from 10 months to 15 years of age, all with severe nutritional problems and in need of a gastrostomy. They all had a history of clinical GER problems including vomiting, choking and chest infections. A 24-h pH monitoring was used for a quantitative assessment of GER the day before surgery and 12+/-3 months (7-22 months) postoperatively. The gastrostomy was placed on the anterior wall of the stomach near the lesser curvature. The main outcome measure was the comparison of the pre- and postoperative 24-h pH monitoring and the reflux index (RI), i.e. the percentage of time with pH below 4. The results showed a non-significant reduction of RI from 6.8+/-4.5 preoperatively to 3.7+/-2.0 postoperatively. We conclude that a gastrostomy using the video-assisted technique and placing the stoma on the anterior wall of the stomach close to the lesser curvature does not cause aggravation of acid reflux.
本研究的目的是评估腹腔镜视频辅助胃造口术对酸性胃食管反流(GER)的影响。一项前瞻性非对照研究纳入了23名神经功能障碍儿童,年龄在10个月至15岁之间,均有严重的营养问题且需要进行胃造口术。他们都有临床GER问题的病史,包括呕吐、呛噎和胸部感染。术前一天及术后12±3个月(7 - 22个月)采用24小时pH监测对GER进行定量评估。胃造口术置于胃小弯附近的前壁。主要结局指标是术前和术后24小时pH监测及反流指数(RI)的比较,即pH低于4的时间百分比。结果显示,RI从术前的6.8±4.5降至术后的3.7±2.0,但差异无统计学意义。我们得出结论,采用视频辅助技术并将造口置于胃小弯附近前壁的胃造口术不会导致酸性反流加重。