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参与一项随机、安慰剂对照试验的非裔美国轻度吸烟者戒烟的预测因素。

Predictors of quitting among African American light smokers enrolled in a randomized, placebo-controlled trial.

作者信息

Nollen Nicole L, Mayo Matthew S, Sanderson Cox Lisa, Okuyemi Kolawole S, Choi Won S, Kaur Harsohena, Ahluwalia Jasjit S

机构信息

Department of Preventive Medicine and Public Health, University of Kansas Medical Center, Kansas City, KS 66160, USA.

出版信息

J Gen Intern Med. 2006 Jun;21(6):590-5. doi: 10.1111/j.1525-1497.2006.00404.x.

Abstract

OBJECTIVE

To examine the predictors of quitting among African American (AA) light smokers (<10 cigarettes per day) enrolled in a smoking cessation trial.

METHODS

Baseline variables were analyzed as potential predictors from a 2 x 2 cessation trial in which participants were randomly assigned to 1 of 4 treatment groups: nicotine gum plus health education (HE) counseling, nicotine gum plus motivational interviewing (MI) counseling, placebo gum plus HE counseling, or placebo gum plus MI counseling. Chi-square tests, 2 sample t-tests, and multiple logistic regression analyses were used to identify predictors of cotinine (COT) verified abstinence at month 6.

RESULTS

In the final regression model, HE rather than MI counseling (odds ratio [OR]=2.26%, 95% confidence interval [CI]=1.36 to 3.74), older age (OR=1.03%, 95% CI=1.01 to 1.06), and higher body mass index (OR=1.04%, 95% CI=1.01 to 1.07) significantly increased the likelihood of quitting, while female gender (OR=0.46%, 95% CI=0.28 to 0.76),</=$1,800/month income (OR=0.60%, 95% CI=0.37 to 0.97), higher baseline COT (OR=0.948%, 95% CI=0.946 to 0.950), and not completing all counseling sessions (OR=0.48%, 95% CI=0.27 to 0.84) reduced the odds of quitting.

CONCLUSIONS

Individual characteristics may decrease the likelihood of quitting; however, the provision of directive, advice-oriented counseling focused on the addictive nature of nicotine, health consequences of smoking, benefits of quitting, and development of a concrete quit plan may be an important and effective facilitator of quitting among AA light smokers.

摘要

目的

研究参加戒烟试验的非裔美国轻度吸烟者(每天吸烟少于10支)戒烟的预测因素。

方法

在一项2×2戒烟试验中,将基线变量作为潜在预测因素进行分析,参与者被随机分配到4个治疗组之一:尼古丁口香糖加健康教育(HE)咨询、尼古丁口香糖加动机访谈(MI)咨询、安慰剂口香糖加HE咨询或安慰剂口香糖加MI咨询。采用卡方检验、两样本t检验和多元逻辑回归分析来确定6个月时可替宁(COT)证实戒烟的预测因素。

结果

在最终回归模型中,HE咨询而非MI咨询(优势比[OR]=2.26%,95%置信区间[CI]=1.36至3.74)、年龄较大(OR=1.03%,95%CI=1.01至1.06)和较高的体重指数(OR=1.04%,95%CI=1.01至1.07)显著增加了戒烟的可能性,而女性(OR=0.46%,95%CI=0.28至0.76)、月收入≤1800美元(OR=0.60%,95%CI=0.37至0.97)、较高的基线COT(OR=0.948%,95%CI=0.946至0.950)以及未完成所有咨询疗程(OR=0.48%,95%CI=0.27至0.84)则降低了戒烟几率。

结论

个体特征可能会降低戒烟的可能性;然而,提供以尼古丁成瘾性、吸烟对健康的影响、戒烟的益处以及制定具体戒烟计划为重点的指导性、以建议为导向的咨询,可能是促进非裔美国轻度吸烟者戒烟的重要且有效的因素。

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